ArticlePediatric nephrology (Berlin, Germany)2014
Acute kidney injury in preterm infants admitted to a neonatal intensive care unit.
Article in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- The global prevalence of acute kidney injury (AKI) in preterm neonates: an epidemiological meta-analysis.European journal of pediatrics · 2026Pooled it
- Acute kidney injury in premature and low birth weight neonates: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Prevalence of acute kidney injury (AKI) in extremely low gestational age neonates (ELGAN).Pediatric nephrology (Berlin, Germany) · 2020Trial
- Neonatal acute kidney injury and the patent ductus arteriosus.Pediatric nephrology (Berlin, Germany) · 2026Review
- Validation of STARZ scoring in very low birth weight (VLBW) neonates in the United States.Pediatric research · 2026Article
- Dialysis modality and mortality of the Contemporary Infant and Neonatal Dialysis (COINED) Cohort: a Pediatric Nephrology Research Consortium (PNRC) study.Pediatric nephrology (Berlin, Germany) · 2026Article
- High early fluid and sodium intake as risk factors for acute kidney injury in very-low-birthweight infants.Pediatric nephrology (Berlin, Germany) · 2026Article
- Interpretable machine learning for the early prediction of acute kidney injury in preterm infants in the neonatal intensive care unit.Renal failure · 2025Article
- Insulin-like growth factor-1 effects on kidney development in preterm piglets.Pediatric research · 2024Article
- Incidence of acute kidney injury and its predictors among neonates admitted at neonatal intensive care unit of, Northwest Ethiopia comprehensive specialized hospitals, 2023.BMC pediatrics · 2024Article
- Risk factors for acute kidney injury in preterm neonates after noncardiac surgery: a single-center retrospective cohort study.Scientific reports · 2024Article
- Incidence and predictors of acute kidney injury among asphyxiated neonates in comprehensive specialized hospitals, northwest Ethiopia, 2023.Scientific reports · 2024Article
- Chronic kidney disease in children: an update.Clinical kidney journal · 2023Review
- Magnitude and associated factors of acute kidney injury among preterm neonates admitted to public hospitals in Bahir Dar city, Ethiopia 2022: cross-sectional study.BMC pediatrics · 2023Article
- Early Mortality in Infants Born with Neonatally Operated Congenital Heart Defects and Low or Very-Low Birthweight: A Systematic Review and Meta-Analysis.Journal of cardiovascular development and disease · 2023Review
- Impact of nephrotoxic drugs on urinary biomarkers of renal function in very preterm infants.Pediatric research · 2022Observational
- Mortality Risk Factors among Infants Receiving Dialysis in the Neonatal Intensive Care Unit.The Journal of pediatrics · 2022Article
- Management of Acute Kidney Injury in Extremely Low Birth Weight Infants.Frontiers in pediatrics · 2022Review
- Vancomycin Use in Children and Neonates across Three Decades: A Bibliometric Analysis of the Top-Cited Articles.Pathogens (Basel, Switzerland) · 2021Review
- Longitudinal Changes in Serum Creatinine Levels and Urinary Biomarkers in Late Preterm Infants during the First Postnatal Week: Association with Acute Kidney Injury and Treatment with Aminoglycoside.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe factors that contribute to the development of acute kidney injury (AKI) and treatment outcome among prematurely born neonates are not clearly understood.
methodsThis retrospective study included 150 prematurely born neonates. AKI was defined as an increase of serum creatinine levels ≥0.3 mg/dl compared to basal values.
resultsThe majority of neonates with AKI (94.8 %) had a body weight <1,500 g. Logistic regression analysis showed that the Apgar score in the 5th minute <5, serum lactate levels >5 on the first day of life, core body temperature <36 ºC on the first day of life, occurrence of sepsis, intracranial hemorrhage, necrotizing enterocolitis, patent ductus arteriosus, as well as a treatment with vancomycin or dopamine were independent risk factors for the development of AKI. After the groups of neonates with and without AKI were adjusted, the calculated risk ratio for a negative outcome of treatment (death) was 2.215 (CI 1.27-3.86) for neonates with AKI. Neonates with AKI had higher serum sodium levels in the third and fourth days of life.
conclusionsAKI is associated with high mortality in preterm neonates. It is very important to identify, as quickly as possible, all infants who are at high risk of developing AKI.
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Registered trials
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