ArticleNeuroradiology2014
Intravoxel incoherent motion perfusion imaging in acute stroke: initial clinical experience.
Article in Neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quantitative estimation of intravoxel incoherent motion parameters in acute ischemic stroke: A Systematic review and meta-analysis.BMC medical imaging · 2025Pooled it
- Multimodal Quantitative MRI of White and Gray Matter: Associations with Myelin-Related Metrics in the Healthy Adult Brain Using Synthetic MRI and IVIM-DWI.Journal of clinical medicine · 2026Article
- No-reflow phenomenon after vessel recanalization in acute ischemic stroke: mechanisms, diagnosis, and treatment directions.Journal of neurology · 2026Review
- Comparative study of image quality, ADC, and IVIM data between multi-b value MUSE-DWI and SS-EPI-DWI in brain imaging.BMC medical imaging · 2025Article
- The Utility of Intravoxel Incoherent Motion Metrics in Assessing Disability in Relapsing-Remitting Multiple Sclerosis.Diagnostics (Basel, Switzerland) · 2025Article
- A Method for Imaging the Ischemic Penumbra with MRI Using Intravoxel Incoherent Motion.AJNR. American journal of neuroradiology · 2025Article
- Investigating the Role of Intravoxel Incoherent Motion Diffusion-Weighted Imaging in Evaluating Multiple Sclerosis Lesions.Diagnostics (Basel, Switzerland) · 2025Article
- Effect of inflammation on neurovascular coupling, microperfusion, and clinical outcomes in ischemic stroke patients: a case series report.Frontiers in medicine · 2025Article
- Intravoxel incoherent motion imaging in stroke infarct core and penumbra is related to long-term clinical outcome.Scientific reports · 2024Article
- Diffusional kurtosis imaging in differentiating nonarteritic anterior ischemic optic neuropathy from acute optic neuritis.Neuroradiology · 2024Article
- Intravoxel incoherent motion (IVIM) detects femoral head ischemia in a piglet model of Legg-Calvé-Perthes disease.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- A supervised deep neural network approach with standardized targets for enhanced accuracy of IVIM parameter estimation from multi-SNR images.NMR in biomedicine · 2022Article
- Crossed cerebellar diaschisis after acute ischemic stroke detected by intravoxel incoherent motion magnetic resonance imaging.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Non-Invasive Evaluation of Cerebral Hemodynamic Changes After Surgery in Adult Patients With Moyamoya Using 2D Phase-Contrast and Intravoxel Incoherent Motion MRI.Frontiers in surgery · 2022Article
- Magnet-targeted delivery of bone marrow-derived mesenchymal stem cells improves therapeutic efficacy following hypoxic-ischemic brain injury.Neural regeneration research · 2021Article
- Mutual constraining of slow component and fast component measures: some observations in liver IVIM imaging.Quantitative imaging in medicine and surgery · 2021Article
- Signal to noise and b-value analysis for optimal intra-voxel incoherent motion imaging in the brain.PloS one · 2021Article
- Article
- Diffusion-weighted MRI of the liver: challenges and some solutions for the quantification of apparent diffusion coefficient and intravoxel incoherent motion.American journal of nuclear medicine and molecular imaging · 2021Review
- Optimized Combination of b‑values for IVIM Perfusion Imaging in Acute Ischemic Stroke Patients.Clinical neuroradiology · 2020Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIntravoxel incoherent motion (IVIM) imaging is an MRI perfusion technique that uses a diffusion-weighted sequence with multiple b values and a bi-compartmental signal model to measure the so-called pseudo-diffusion of blood caused by its passage through the microvascular network. The goal of the current study was to assess the feasibility of IVIM perfusion fraction imaging in patients with acute stroke.
methodsImages were collected in 17 patients with acute stroke. Exclusion criteria were onset of symptoms to imaging >5 days, hemorrhagic transformation, infratentorial lesions, small lesions <0.5 cm in minimal diameter and hemodynamic instability. IVIM imaging was performed at 3 T, using a standard spin-echo Stejskal-Tanner pulsed gradients diffusion-weighted sequence, using 16 b values from 0 to 900 s/mm(2). Image quality was assessed by two radiologists, and quantitative analysis was performed in regions of interest placed in the stroke area, defined by thresholding the apparent diffusion coefficient maps, as well as in the contralateral region.
resultsIVIM perfusion fraction maps showed an area of decreased perfusion fraction f in the region of decreased apparent diffusion coefficient. Quantitative analysis showed a statistically significant decrease in both IVIM perfusion fraction f (0.026 ± 0.019 vs. 0.056 ± 0.025, p=2.2 · 10(-6)) and diffusion coefficient D compared with the contralateral side (3.9 ± 0.79 · 10(-4) vs. 7.5 ± 0.86 · 10(-4) mm(2)/s, p=1.3 · 10(-20)).
conclusionIVIM perfusion fraction imaging is feasible in acute stroke. IVIM perfusion fraction is significantly reduced in the visible infarct. Further studies should evaluate the potential for IVIM to predict clinical outcome and treatment response.
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