Evidence map›Paper›PMID 24838593›Full record

ReviewNeurourology and urodynamics2014

Does our limited knowledge of the mechanisms of neural stimulation limit its benefits for patients with overactive bladder? ICI-RS 2013.

Jerzy B Gajewski, Anthony J Kanai, Linda Cardozo, Youko Ikeda, Irina V Zabbarova

Open access · greenAbstract readReview
In one paragraph

Review in Neurourology and urodynamics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Jerzy B GajewskiDalhousie University, Halifax, Nova Scotia, Canada.
Anthony J Kanai
Linda Cardozo
Youko Ikeda
Irina V Zabbarova
University of Pittsburgh · USDalhousie University · CAUniversity of Cambridge · GB

Funding

Urothelium in Detrusor OveractivityP01DK093424 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEGROAT, WILLIAM C · 2013 to 2017
$7.9M
PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse BladdersR01DK098361 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, KANAI, ANTHONY JOHN · 2014 to 2024
$5.7M
Roles of Nitric Oxide and Superoxide in CystitisR01DK071085 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KANAI, ANTHONY JOHN · 2005 to 2017
$3.3M
NIDDK NIH HHS P01 DK093424NIDDK NIH HHS R01 DK071085NIDDK NIH HHS R01 DK098361
6 · The paper itself

Abstract

introductionNeural stimulation has become an established minimally invasive treatment for various lower urinary tract symptoms. The results both short- and long-term are encouraging, however, there is still a lack of knowledge of obvious risk factors, which may affect the outcome of treatment. Although neural stimulation has been embraced by healthcare professionals and patients, the exact mechanism by which neural stimulation works is still unclear. DISCUSSION: A condense review of knowledge available on this topic is presented. Several research questions are raised. Outlines of research studies, both clinical and basic science, are suggested.

conclusionsFurther studies are necessary to understand mechanism of action of neural stimulation and its implications on treatment outcomes.

Indexed as

Electric Stimulation TherapyLumbosacral PlexusPudendal NerveTibial NerveHumansLower Urinary Tract SymptomsTranscutaneous Electric Nerve StimulationTreatment OutcomeUrinary Bladder, Overactiveneural stimulationoveractive bladder

Identifiers

PMID24838593
PMCPMC5515467
OpenAlexW1898769794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.