Evidence map›Paper›PMID 24838356›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2014

[Renal replacement therapy as a possible trauma in acute kidney injury].

S John

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. [Lung and kidney failure. Pathogenesis, interactions, and therapy].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2015
    Review
  2. [Adsorption therapy in sepsis].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2015
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

S JohnMedizinische Klinik 4, Universität Erlangen-Nürnberg, Breslauer Str. 201, 90471, Nürnberg, Deutschland, stefan.john@uk-erlangen.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal replacement therapy (RRT) is not able to replace all of the physiologic functions of the kidney. Moreover renal replacement therapy can be associated with a number of serious side effects and complications which can alter the natural course and prognosis of critically ill patients. PROBLEM: Contributing to this RRT trauma are hemodynamic changes induced by RRT, the induction of inflammation by the extracorporeal circuit itself, side effects of anticoagulation, but especially often unwanted and not recognized losses of multiple substances by the blood purification itself.

aimTherefore, the aim should be to adapt therapy in a way that systemic and renal side effects can be minimized or replaced. These include the correct selection of the RRT modality for each patient and each individual clinical situation, in prescribing and monitoring an individual dose of RRT, and the substitution of unwanted losses of different substances. Especially in septic patients, antimicrobials have to be prescribed carefully during the first 72 h, during which underdosing of these substances is a real danger in patients on renal replacement therapy.

Indexed as

Acute Kidney InjuryAnti-Bacterial AgentsAnticoagulantsHemodynamicsHumansInflammation MediatorsPrecision MedicineRenal Replacement TherapyRisk FactorsSepsisAnti-Bacterial AgentsAnticoagulantsInflammation Mediators

Identifiers

PMID24838356
OpenAlexW2151574730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.