Evidence map›Paper›PMID 24837762›Full record

ArticleVaccine2014

Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011.

E Anthony S Nelson, Margaret Ip, John S Tam, Anthony W Mounts, Sze Lok Chau, Shu Kei Law, William Goggins, Lucy A Simpson, Paul K S Chan

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

E Anthony S NelsonDepartment of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address: tony-nelson@cuhk.edu.hk.
Margaret IpDepartment of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong,Hong Kong Special Administrative Region. Electronic address: margaretip@cuhk.edu.hk.
John S TamInitiative for Vaccine Research (IVR), Department of Immunization, Vaccines and Biologicals (IVB), Family and Community Health (FCH), Geneva, Switzerland. Electronic address: johntam64@yahoo.com.
Anthony W MountsGlobal Influenza Programme, Department of Pandemic and Epidemic Diseases (PED), World Health Organization, Geneva, Switzerland. Electronic address: mountsa@who.int.
Sze Lok ChauDepartment of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong,Hong Kong Special Administrative Region. Electronic address: kfszelok@gmail.com.
Shu Kei LawDivision of Biostatistics, School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address: b113641@mailserv.cuhk.edu.hk.
William GogginsDivision of Biostatistics, School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address: wgoggins@cuhk.edu.hk.
Lucy A SimpsonDepartment of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address: lucysimpson@me.com.
Paul K S ChanDepartment of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong,Hong Kong Special Administrative Region. Electronic address: paulkschan@cuhk.edu.hk.
Chinese University of Hong Kong · HKWorld Health Organization · CH

Funding

PHS HHS 5U50C1000748World Health Organization 001
6 · The paper itself

Abstract

The World Health Organization recommends vaccination of pregnant women for seasonal influenza that can also protect infants aged below 6 months. We estimated incidence and disease burden of influenza in hospitalised children below and above 6 months of age in Hong Kong during a 6 year period. Discharge diagnoses for all admissions to public Hong Kong Hospital Authority hospitals, recorded in a central computerised database (Clinical Management System, CMS), were analysed for the period April 2005 to March 2011. Incidence estimates of influenza disease by age group were derived from CMS ICD codes 487-487.99. Laboratory-confirmed influenza infections from a single surveillance hospital were then linked to the CMS entries to assess possible over- and under-diagnosis of influenza based on CMS codes alone. Influenza was recorded as any primary or any secondary diagnosis in 1.3% (1158/86,582) of infants aged above 6 days to below 6 months and 4.3% (20,230/471,482) of children above 6 days to below 18 years. The unadjusted incidence rates per 100,000 person-years based on any CMS diagnosis of influenza in all admission to Hong Kong public hospitals were 627 in the below 2 months of age group and 1762 in the 2 month to below 6 month group. Incidence of hospitalisation for influenza in children was highest from 2 months to below 6 months. In the absence of vaccines for children below 6 months of age, effective vaccination of pregnant women may have a significant impact on reducing influenza hospitalisations in this age group.

Indexed as

Cost of IllnessHospitalizationAdolescentChildChild, PreschoolFemaleHong KongHumansIncidenceInfantInfant, NewbornInfluenza, HumanMalePregnancyChildrenDisease burdenHospitalisationInfantsInfluenza

Identifiers

PMID24837762
PMCPMC5355210
OpenAlexW2008664722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.