Evidence map›Paper›PMID 24837173›Full record

ArticleEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery2014

Comparison of three contemporary risk scores for mortality following elective abdominal aortic aneurysm repair.

S W Grant, G L Hickey, E D Carlson, C N McCollum

Abstract readComparative StudyMulticenter StudyValidation Study
In one paragraph

Article in European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

S W GrantThe University of Manchester, Manchester Academic Health Science Centre, UHSM, Academic Surgery Unit, Education and Research Centre, Manchester, UK; University College London, National Institute for Cardiovascular Outcomes Research, Institute of Cardiovascular Science, London, UK. Electronic address: stuart.grant@manchester.ac.uk.
G L HickeyUniversity College London, National Institute for Cardiovascular Outcomes Research, Institute of Cardiovascular Science, London, UK; The University of Manchester, Manchester Academic Health Science Centre, Centre for Health Informatics, Manchester, UK.
E D CarlsonThe University of Manchester, Manchester Academic Health Science Centre, UHSM, Academic Surgery Unit, Education and Research Centre, Manchester, UK.
C N McCollumThe University of Manchester, Manchester Academic Health Science Centre, UHSM, Academic Surgery Unit, Education and Research Centre, Manchester, UK.

Funding

Department of Health 09/91/39
6 · The paper itself

Abstract

OBJECTIVE/

backgroundA number of contemporary risk prediction models for mortality following elective abdominal aortic aneurysm (AAA) repair have been developed. Before a model is used either in clinical practice or to risk-adjust surgical outcome data it is important that its performance is assessed in external validation studies.

methodsThe British Aneurysm Repair (BAR) score, Medicare, and Vascular Governance North West (VGNW) models were validated using an independent prospectively collected sample of multicentre clinical audit data. Consecutive, data on 1,124 patients undergoing elective AAA repair at 17 hospitals in the north-west of England and Wales between April 2011 and March 2013 were analysed. The outcome measure was in-hospital mortality. Model calibration (observed to expected ratio with chi-square test, calibration plots, calibration intercept and slope) and discrimination (area under receiver operating characteristic curve [AUC]) were assessed in the overall cohort and procedural subgroups.

resultsThe mean age of the population was 74.4 years (SD 7.7); 193 (17.2%) patients were women and the majority of patients (759, 67.5%) underwent endovascular aneurysm repair. All three models demonstrated good calibration in the overall cohort and procedural subgroups. Overall discrimination was excellent for the BAR score (AUC 0.83, 95% confidence interval [CI] 0.76-0.89), and acceptable for the Medicare and VGNW models, with AUCs of 0.78 (95% CI 0.70-0.86) and 0.75 (95% CI 0.65-0.84) respectively. Only the BAR score demonstrated good discrimination in procedural subgroups.

conclusionAll three models demonstrated good calibration and discrimination for the prediction of in-hospital mortality following elective AAA repair and are potentially useful. The BAR score has a number of advantages, which include being developed on the most contemporaneous data, excellent overall discrimination, and good performance in procedural subgroups. Regular model validations and recalibration will be essential.

Indexed as

Decision Support TechniquesAgedAged, 80 and overAortic Aneurysm, AbdominalArea Under CurveBlood Vessel Prosthesis ImplantationChi-Square DistributionDiscriminant AnalysisElective Surgical ProceduresEndovascular ProceduresEnglandFemaleHospital MortalityHumansMaleMedical AuditAbdominal aortic aneurysmClinical prediction ruleIn-hospital mortalityRisk adjustment

Identifiers

PMID24837173
PMCPMC4082141

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.