Evidence map›Paper›PMID 24835507›Full record

SynthesisEnvironmental health perspectives2014

Arterial blood pressure and long-term exposure to traffic-related air pollution: an analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE).

Kateryna B Fuks, Gudrun Weinmayr, Maria Foraster, Julia Dratva, Regina Hampel, Danny Houthuijs, Bente Oftedal, Anna Oudin, Sviatlana Panasevich, Johanna Penell and 49 more

Open access · diamondAbstract readMeta-Analysis
In one paragraph

Synthesis in Environmental health perspectives, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.

  1. Pooled it
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  12. Traffic related activity pattern of Chinese adults: a nation-wide population based survey.Journal of exposure science & environmental epidemiology · 2023
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  20. The effect of short term exposure to outdoor air pollution on fertility.Reproductive biology and endocrinology : RB&E · 2021
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

59 authors at 20 institutions in 9 countries.

Kateryna B FuksIUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
Gudrun Weinmayr
Maria Foraster
Julia Dratva
Regina Hampel
Danny Houthuijs
Bente Oftedal
Anna Oudin
Sviatlana Panasevich
Johanna Penell
Johan N Sommar
Mette Sørensen
Pekka Tiittanen
Kathrin Wolf
Wei W Xun
Inmaculada Aguilera
Xavier Basagaña
Rob Beelen
Michiel L Bots
Bert Brunekreef
H Bas Bueno-de-Mesquita
Barbara Caracciolo
Marta Cirach
Ulf de Faire
Audrey de Nazelle
Marloes Eeftens
Roberto Elosua
Raimund Erbel
Bertil Forsberg
Laura Fratiglioni
Jean-Michel Gaspoz
Agneta Hilding
Antti Jula
Michal Korek
Ursula Krämer
Nino Künzli
Timo Lanki
Karin Leander
Patrik K E Magnusson
Jaume Marrugat
Mark J Nieuwenhuijsen
Claes-Göran Ostenson
Nancy L Pedersen
Göran Pershagen
Harish C Phuleria
Nicole M Probst-Hensch
Ole Raaschou-Nielsen
Emmanuel Schaffner
Tamara Schikowski
Christian Schindler
Per E Schwarze
Anne J Søgaard
Dorothea Sugiri
Wim J R Swart
Ming-Yi Tsai
Anu W Turunen
Paolo Vineis
Annette Peters
Barbara Hoffmann
Karolinska Institutet · SESwiss Tropical and Public Health Institute · CHCenter for Research in Environmental Epidemiology · ESFinnish Institute for Health and Welfare · FILeibniz Institute of Environmental Medicine · DENorwegian Institute of Public Health · NOHelmholtz Zentrum München · DENational Institute for Public Health and the Environment · NLUmeå University · SEUtrecht University · NLDanish Cancer Society · DKHospital Del Mar · ESStockholm University · SEDeutsches Herzzentrum München · DEImperial College London · GBUniversitat Pompeu Fabra · ESUniversität Ulm · DEUniversity College London · GBUniversity Medical Center Utrecht · NLUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term exposure to air pollution has been hypothesized to elevate arterial blood pressure (BP). The existing evidence is scarce and country specific.

objectivesWe investigated the cross-sectional association of long-term traffic-related air pollution with BP and prevalent hypertension in European populations.

methodsWe analyzed 15 population-based cohorts, participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE). We modeled residential exposure to particulate matter and nitrogen oxides with land use regression using a uniform protocol. We assessed traffic exposure with traffic indicator variables. We analyzed systolic and diastolic BP in participants medicated and nonmedicated with BP-lowering medication (BPLM) separately, adjusting for personal and area-level risk factors and environmental noise. Prevalent hypertension was defined as ≥ 140 mmHg systolic BP, or ≥ 90 mmHg diastolic BP, or intake of BPLM. We combined cohort-specific results using random-effects meta-analysis.

resultsIn the main meta-analysis of 113,926 participants, traffic load on major roads within 100 m of the residence was associated with increased systolic and diastolic BP in nonmedicated participants [0.35 mmHg (95% CI: 0.02, 0.68) and 0.22 mmHg (95% CI: 0.04, 0.40) per 4,000,000 vehicles × m/day, respectively]. The estimated odds ratio (OR) for prevalent hypertension was 1.05 (95% CI: 0.99, 1.11) per 4,000,000 vehicles × m/day. Modeled air pollutants and BP were not clearly associated.

conclusionsIn this first comprehensive meta-analysis of European population-based cohorts, we observed a weak positive association of high residential traffic exposure with BP in nonmedicated participants, and an elevated OR for prevalent hypertension. The relationship of modeled air pollutants with BP was inconsistent.

Indexed as

Arterial PressureAir PollutantsAir PollutionAntihypertensive AgentsCross-Sectional StudiesEnvironmental ExposureEuropeFemaleHumansHypertensionMaleNitrogen OxidesNoise, TransportationParticulate MatterRisk FactorsVehicle EmissionsAir PollutantsAntihypertensive AgentsNitrogen OxidesParticulate MatterVehicle Emissions

Identifiers

PMID24835507
PMCPMC4154218
OpenAlexW1966533725

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.