ArticleMedical science monitor : international medical journal of experimental and clinical research2014
Seasonality pattern of breast, colorectal, and prostate cancer is dependent on latitude.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Gonorrhea and Prostate Cancer Incidence: An Updated Meta-Analysis of 21 Epidemiologic Studies.Medical science monitor : international medical journal of experimental and clinical research · 2015Pooled it
- Cardio-Oncology in Cold Climates: Epidemiological Features, Bidirectional Interaction Mechanisms, and Integrated Management Strategies.Cardiovascular toxicology · 2026Review
- Is Season of Diagnosis a Predictor of Cancer Survival? Results from the Zurich Cancer Registry.Nutrients · 2022Article
- Article
- The Contrasting Seasonality Patterns of Some Cancer-Types and Herpes Zoster Can Be Explained by a Binary Classification of Immunological Reactions.Journal of inflammation research · 2022Article
- Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California.Nature communications · 2020Article
- Nutrigenomics and Breast Cancer: State-of-Art, Future Perspectives and Insights for Prevention.Nutrients · 2020Review
- A multicenter case control study of association of vitamin D with breast cancer among women in Karachi, Pakistan.PloS one · 2020Article
- The Vitamin D⁻Folate Hypothesis as an Evolutionary Model for Skin Pigmentation: An Update and Integration of Current Ideas.Nutrients · 2018Review
- Gene expression profiling analysis of castration-resistant prostate cancer.Medical science monitor : international medical journal of experimental and clinical research · 2015Article
- Aberrant methylation of protocadherin 17 and its clinical significance in patients with prostate cancer after radical prostatectomy.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Aberrant methylation of PCDH10 predicts worse biochemical recurrence-free survival in patients with prostate cancer after radical prostatectomy.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe season of diagnosis of several forms of cancer has been observed to impact survival, supporting the hypothesis that vitamin D3 has a protective role in cancer survival. All previous studies demonstrating this seasonality were performed in European populations residing at latitudes upwards of 50°N. This study investigated whether seasonality of prognosis persists in populations residing in the lower latitudes of the contiguous United States (Latitude 21°N to 48°N). MATERIAL/
methodsThe 5-year survival data of 19 204 female breast cancer, 6740 colorectal cancer, and 1644 prostate cancer cases was analyzed.
resultsFemale breast cancer patients exhibited improved survival when diagnosed in the summer as compared to the winter at all latitudes (Hazard Ratio [HR]: 0.940, 95%; Confidence Interval [CI]: 0.938 to 0.941, P=0.002). Colorectal cancer and prostate cancer also exhibited a similar seasonal pattern (HR: 0.978, 95% CI: 0.975 to 0.980, P=0.008 and HR: 0.935, 95%, CI 0.929 to 0.943, P=0.006), respectively, when the analysis was restricted to northern regions.
conclusionsThese observations contribute to the mounting evidence that vitamin D3 may affect the progression of cancer. Data also suggest that vitamin D3 status at the onset of treatment may synergistically improve the prognosis of several cancer types.
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