Evidence map›Paper›PMID 24834425›Full record

ArticleQuantitative imaging in medicine and surgery2014

In vivo diffusion spectrum imaging of non-human primate brain: initial experience in transcallosal fiber examination.

Yuguang Meng, Xiaodong Zhang

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Parallel and sparse MR imaging: methods and instruments-Part 2.Quantitative imaging in medicine and surgery · 2014
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuguang Meng1 Yerkes Imaging Center, 2 Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.
Xiaodong Zhang1 Yerkes Imaging Center, 2 Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
YNPRC NHP CLINICAL MEDICINE RESIDENCY PROGRAM - SUPPLEMENTP51RR000165 · NCRR · EMORY UNIVERSITY · PI ALTMAN, JOHN DAVID · 1985 to 2011
$114.0M
NCRR NIH HHS P51 RR000165NIH HHS P51 OD011132
6 · The paper itself

Abstract

In comparison with conventional diffusion tensor imaging (DTI) technique, diffusion spectrum imaging (DSI) allows for delineating crossing and touching fibers in the brain and has been explored in clinical and preclinical studies. Non-human primates (NHPs) resemble most aspects of human and are widely employed in various neuroscience researches and pharmaceutical development. In the present study, a parallel imaging-based DSI protocol was implemented for in vivo fiber tracking of macaque monkey brains on a 3.0 T clinical scanner. Transcallosal fiber tracts of adult macaque brains were examined with DSI and compared with those from a a conventional DTI protocol. The results demonstrate that DSI can reveal the transcallosal fiber bundles much more extensively than the conventional DTI. The preliminary results suggest that DSI may provide a feasible and robust approach for characterizing the fiber pathways in various disease models of NHPs.

Indexed as

diffusion spectrum imaging (DSI)diffusion tensor imaging (DTI)In vivomacaque monkeystranscallosal fibers

Identifiers

PMID24834425
PMCPMC4014874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.