ArticleSpringerPlus2014
Cinnarizine for the prophylaxis of migraine associated vertigo: a retrospective study.
Article in SpringerPlus, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Vestibular migraine treatment: a comprehensive practical review.Brain : a journal of neurology · 2022Pooled it
- Bariatric Surgery Promising in Migraine Control: a Controlled Trial on Weight Loss and Its Effect on Migraine Headache.Obesity surgery · 2018Trial
- Vestibular Migraine Revisited: A Narrative Review of Diagnostic Challenges and Treatment Strategies.The journal of international advanced otology · 2025Review
- Recent Trends in Treatment of Vestibular Migraine: A Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Vestibular Migraine Pathophysiology and Treatment: a Narrative Review.Current pain and headache reports · 2024Review
- Case Series: Vestibular Migraines in Fragile X Premutation Carriers.Journal of clinical medicine · 2024Article
- Histaminergic System and Vestibular Function in Normal and Pathological Conditions.Current neuropharmacology · 2024Review
- Good response to rectal diazepam in refractory cases of cyclic vomiting: A case-series and review of the literature.Clinical case reports · 2023Article
- Migraine management for the otolaryngologist.Laryngoscope investigative otolaryngology · 2023Review
- Vestibular migraine in low- and lower-middle-income countries: A scoping review.Journal of otology · 2023Article
- Treating Vestibular Migraine When Pregnant and Postpartum: Progress, Challenges and Innovations.International journal of women's health · 2023Review
- The Pharmacological Treatment of Pediatric Vertigo.Children (Basel, Switzerland) · 2022Review
- Synthesis of medicinally relevant oxalylamines via copper/Lewis acid synergistic catalysis.Science advances · 2021Article
- Vestibular migraine: the chameleon in vestibular disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Review
- Pharmacogenetics in Primary Headache Disorders.Frontiers in pharmacology · 2021Review
- Management of peripheral vertigo with antihistamines: New options on the horizon.British journal of clinical pharmacology · 2019Review
- Current Treatment Options: Vestibular Migraine.Current treatment options in neurology · 2017Review
- The Efficacy of Venlafaxine, Flunarizine, and Valproic Acid in the Prophylaxis of Vestibular Migraine.Frontiers in neurology · 2017Article
- Acetazolamide in vestibular migraine prophylaxis: a retrospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Article
- Vestibular migraine: the most frequent entity of episodic vertigo.Journal of neurology · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the efficacy and safety of cinnarizine for the prophylaxis of migraine associated vertigo in the vestibular migraine and migraine with brainstem aura.
backgroundVestibular migraine and migraine with brainstem aura are two principal clinical syndromes that frequently are associated with vertigo. Since cinnarizine is a well-tolerated calcium channel blocker which has acceptable effect on both vertigo and migraine headache, we carried out this study to evaluate the efficacy and safety of this medication in vestibular migraine and also migraine with brainstem aura associated with vertigo.
methodsThis was a retrospective, single-center, open-label, investigation of the effects of cinnarizine on vestibular migraine and migraine with associated with vertigo. We assessed the change in monthly frequency of vertigo and also frequency, duration and intensity of migraine attacks after one, two and three months of cinnarizine administration.
resultsThe mean frequency of vertigo and also the mean frequency, duration and intensity of migraine headaches per month were reduced significantly after three months of cinnarizine therapy (all p < 0.001).
conclusionThis study suggests that cinnarizine is safe and effective in reducing both headache and vertigo aspects of "migraine plus vertigo" among the patients who suffer from either vestibular migraine or migraine with brainstem aura associated with vertigo.
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Registered trials
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