Evidence map›Paper›PMID 24834235›Full record

ArticleGastroenterology and hepatology from bed to bench2012

Using statistical models to assess medical cost of hepatitis C virus.

Mohsen Vahedi, Asma Pourhoseingholi, Sara Ashtari, Mohamad Amin Pourhoseingholi, Maryam Karkhane, Bijan Moghimi-Dehkordi, Azadeh Safaee, Zahra Kimia, Seyed Moayed Alavian

Abstract read
In one paragraph

Article in Gastroenterology and hepatology from bed to bench, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Estimation of average diagnosis and treatment costs of hepatitis C.Gastroenterology and hepatology from bed to bench · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohsen VahediDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Asma PourhoseingholiDepartment of Biostatistics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sara AshtariResearch Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohamad Amin PourhoseingholiDepartment of Biostatistics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Maryam KarkhaneResearch Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Bijan Moghimi-DehkordiResearch Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azadeh SafaeeResearch Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahra KimiaResearch Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Moayed AlavianBaqiyatallah Research Center for Gastroenterology and Liver Disease, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study compared PR and NB in predicting HCV patient costs. The objective of this study was to predict the direct cost of the HCV patient in Iran.

backgroundHepatitis C virus (HCV) is a common and expensive infectious disease in Iran. Cost associated with HCV and its complications has not been well characterized. Analysis of cost data is important in providing consistent information to aid budgeting decisions and certain statistical regression models need for prediction mean costs. Poisson regression (PR) and negative binomial regression (NB) are more common in cost prediction study. PATIENTS AND

methodsThis study designed as a cross-sectional clinic base from 2001 to 2010. First treatment period of each patient bring in study. We evaluated the doctor visiting, drugs, and hospitalization and laboratory tests of patients. Cost per person per one treatment period estimated in purchasing power parity dollars (PPP$). The PR is one of the models from general linear models (GLM) for describing count outcomes. The NB is another model from (GLM) as an alternative to the PR model.

resultsAccording to Likelihood ratio test NB was found to be more appropriate than PR (P < 0.001). Genotype, marriage, medication, and SVR were being significant. Genotype 3 versus 1 decreasing cost while marriage, consuming pegasys and SVR increasing.

conclusionChoosing best model in cost data is important because of specific feature of this data. After fitting the best model, analyzing and predicting future cost for patient in different situation is possible.

Indexed as

Chronic hepatitis CCostsNegative binomial regressionPoisson regressionPredictive models

Identifiers

PMID24834235
PMCPMC4017486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.