Evidence map›Paper›PMID 24834216›Full record

ArticleGastroenterology and hepatology from bed to bench2012

Microscopic Enteritis; clinical features and correlations with symptoms.

Touran Shahraki, Kamran Rostami, Mansour Shahraki, Justine Bold, Mihai Danciu, David Al Dulaimi, Vincenzo Villanacci, Gabrio Bassotti

Open access · greenAbstract read
In one paragraph

Article in Gastroenterology and hepatology from bed to bench, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Microscopic enteritis: Bucharest consensus.World journal of gastroenterology · 2015
    Guideline
  2. Review
  3. Article
  4. What is the best histopathological classification for celiac disease? Does it matter?Gastroenterology and hepatology from bed to bench · 2015
    Article
  5. Coeliac disease: changing diagnostic criteria?Gastroenterology and hepatology from bed to bench · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Touran ShahrakiDepartment of Pediatrics, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Kamran RostamiSchool of Clinical and Experimental Medicine, University of Birmingham, United Kingdom.
Mansour ShahrakiDepartment of Nutrition, and Research Center for Children and Adolescent Health, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Justine BoldInstitute of Health, Social Care and Psychology University of Worcester UK.
Mihai DanciuDepartment of Pathology, University of Medicine and Pharmacy Iasi, Romania.
David Al DulaimiDepartment of Gastroenterology, Alexander Hospital, Redditch, UK.
Vincenzo Villanacci2nd Department of Pathology, Spedali Civili University of Brescia Italy.
Gabrio BassottiGastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy.
Alexandra Hospital · GBUniversity of Birmingham · GBUniversity of Perugia · ITZahedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the clinical characteristic of CD as well as correlation of symptoms and the degrees of intestinal mucosal lesions in Iranian children.

backgroundMicroscopic Enteritis (Marsh 0-II) is associated with malabsorption. PATIENTS AND

methodsFrom August 2005 to September 2009, 111 cases with malabsorption and classical gastrointestinal symptoms were evaluated.

resultsThe mean (±SD) age of children with CD was 4.9±3.5 years (range, 6 month - 16 years) and the mean duration of symptoms was 8 ± 20.5 months. 50 cases (45%) were female and 61 cases (55%) were male. The most common clinical presentation was failure to thrive in 72%, chronic diarrhea in 65.8% and Iron deficiency anemia in 59.5%. Sensitivity of EMA was 100% in patients with Marsh IIIb and Marsh IIIc. EMA was also positive in 77% of cases with Marsh 0, 18% in Marsh I, 44% in Marsh II and 81.8% in patients with Marsh IIIa.

conclusionHistopathology did not reflect the severity of gluten sensitivity. This would suggest that the degree of intestinal mucosal damage might not be a reliable prognostic factor. Significant symptoms can be present with minor histological change on biopsy.

Indexed as

Coeliac diseaseHistologyMacroscopic enteritisSerology

Identifiers

PMID24834216
PMCPMC4017477
OpenAlexW1562136027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.