Evidence map›Paper›PMID 24833944›Full record

ReviewClinical medicine insights. Gastroenterology2014

Virulence Factors of Helicobacter pylori: A Review.

Bruna M Roesler, Elizabeth M A Rabelo-Gonçalves, José M R Zeitune

Registry-linked trialAbstract readReview
In one paragraph

Review in Clinical medicine insights. Gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02317445 (Beijing Tiantan Hospital,Capital Medical University.), which is not on this map. Cited by 72 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02317445 completednot on this map

Beijing Tiantan Hospital,Capital Medical University.

TypeobservationalSponsorCapital Medical UniversityRan2008 to 2013Enrolled472ConditionsAcute Coronary Syndrome
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Frontiers in medicine · 2026
    Pooled it
  2. Pooled it
  3. BMJ open gastroenterology · 2020
    Pooled it
  4. Review
  5. Article
  6. Clinical Pathologic Profiles ofJournal of clinical medicine · 2025
    Article
  7. Review
  8. Beyond the stomach: the association betweenFrontiers in cellular and infection microbiology · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Prevalence and virulence factors ofJournal of dental sciences · 2024
    Article
  13. International journal of biological sciences · 2024
    Article
  14. The immunopathogenesis ofFrontiers in microbiology · 2024
    Review
  15. Article
  16. Dysbiosis by Eradication ofMicroorganisms · 2023
    Article
  17. High-Salt Diet ExacerbatesJournal of personalized medicine · 2023
    Review
  18. Review
  19. International journal of molecular sciences · 2023
    Review
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bruna M RoeslerDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil. ; Center of Diagnosis of Digestive Diseases, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil.
Elizabeth M A Rabelo-GonçalvesDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil. ; Center of Diagnosis of Digestive Diseases, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil.
José M R ZeituneDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil. ; Center of Diagnosis of Digestive Diseases, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori is a spiral-shaped Gram-negative bacterium that colonizes the human stomach and can establish a long-term infection of the gastric mucosa, a condition that affects the relative risk of developing various clinical disorders of the upper gastrointestinal tract, such as chronic gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric adenocarcinoma. H. pylori presents a high-level of genetic diversity, which can be an important factor in its adaptation to the host stomach and also for the clinical outcome of infection. There are important H. pylori virulence factors that, along with host characteristics and the external environment, have been associated with the different occurrences of diseases. This review is aimed to analyzing and summarizing the main of them and possible associations with the clinical outcome.

Indexed as

chronic gastritisgastric adenocarcinomaHelicobacter pyloripeptic ulcer diseasevirulence factors

Identifiers

PMID24833944
PMCPMC4019226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.