ReviewWorld journal of gastroenterology2014
Culture-guided treatment approach for Helicobacter pylori infection: review of the literature.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Eradication efficacy of empiric bismuth quadruple therapy containing amoxicillin in the first-line treatment of Helicobacter pylori in Ningxia, China.BMC gastroenterology · 2026Article
- Amoxicillin, gemifloxacin and rabeprazole, as first-line Helicobacter pylori therapy in clinical practice: A pilot study.Medicine · 2024Article
- Effect of an individualized bismuth quadruple regimen guided by 10-day or 14-day antibiotic susceptibility testing for first-line eradication treatment ofFrontiers in medicine · 2024Article
- Sequential therapy versus quadruple therapy forHealth science reports · 2024Article
- The Influence ofAntibiotics (Basel, Switzerland) · 2023Review
- Article
- Empirical vs. Susceptibility-Guided Treatment ofFrontiers in microbiology · 2022Article
- Antibiotic Resistance Prevalence and Trends in Patients Infected withAntibiotics (Basel, Switzerland) · 2021Article
- Detection of Helicobacter pylori by invasive tests in adult dyspeptic patients and antibacterial resistance to six antibiotics, including rifampicin in Turkey. Is clarithromycin resistance rate decreasing?Turkish journal of medical sciences · 2021Article
- Role of Antimicrobial Susceptibility Testing before First-Line Treatment Containing Clarithromycin forAntibiotics (Basel, Switzerland) · 2021Article
- Empirical or susceptibility-guided treatment forTherapeutic advances in gastroenterology · 2020Review
- Optimizing proton pump inhibitors inWorld journal of gastroenterology · 2019Review
- Comparison of Levofloxacin-Based, 10-day Sequential Therapy with 14-day Quadruple Therapy forMiddle East journal of digestive diseases · 2018Article
- Current Status of the Third-LineGastroenterology research and practice · 2018Review
- Are the view of Helicobacter pylori colonized in the oral cavity an illusion?Experimental & molecular medicine · 2017Review
- In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules.Nature communications · 2017Article
- Importance of antimicrobial susceptibility testing for the management of eradication inWorld journal of gastroenterology · 2017Review
- Rifabutin-based 10-day and 14-day triple therapy as a third-line and fourth-line regimen for Helicobacter pylori eradication: how should rifabutin be managed in rescue regimens?United European gastroenterology journal · 2016Article
- Helicobacter pylori colonization of the oral cavity: A milestone discovery.World journal of gastroenterology · 2016Review
- Response to: Comment on "Efficacy of 7-Day and 14-Day Triple Therapy Regimens for the Eradication of Helicobacter pylori: A Comparative Study in a Cohort of Romanian Patients".Gastroenterology research and practice · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The progressive loss of efficacy of standard eradication therapies has made the treatment of Helicobacter pylori (H. pylori) more challenging than ever. Endoscopic-guided antibiotic susceptibility testing had previously been suggested to guide treatment after failure of second-line therapies. However, its role has expanded over the years, in accordance with the current Maastricht Guidelines. Several authors have dealt with this topic, developing both efficacy trials and cost-effectiveness trials against resistant H. pylori infections as well as infections in naïve patients. However, results are not homogeneous enough to provide definite advice, because antibiotic resistance is not the only reason for treatment failure. Moreover, the culture-guided approach is surrounded by many practical issues, such as the availability of both endoscopy units and microbiology laboratories, and the need for a standard of quality that cannot be satisfied everywhere. Finally, pre-treatment susceptibility testing should be part - and not the only weapon - of a targeted, personalized strategy to overcome H. pylori infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.