Evidence map›Paper›PMID 24833818›Full record

ArticleUrology annals2014

Extended-spectrum beta-lactamase-positive Escherichia coli causing complicated upper urinary tract infection: Urologist should act in time.

Stefano C M Picozzi, Stefano Casellato, Mattia Rossini, Gaia Paola, Milvana Tejada, Elena Costa, Luca Carmignani

Open access · goldAbstract read
In one paragraph

Article in Urology annals, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Extended-SpectrumInterdisciplinary perspectives on infectious diseases · 2020
    Article
  13. Article
  14. Article
  15. Antibiotic-resistantThe Indian journal of medical research · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stefano C M PicozziDepartment of Urology, Service Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
Stefano CasellatoDepartment of Urology, Service Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
Mattia RossiniDepartment of Urology, Service Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
Gaia PaolaDepartment of Laboratory Medicine Service - Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
Milvana TejadaDepartment of Laboratory Medicine Service - Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
Elena CostaDepartment of Laboratory Medicine Service - Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
Luca CarmignaniDepartment of Urology, Service Section of Microbiology, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097-San Donato Milanese, Milan, Italy.
IRCCS Policlinico San Donato · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecently, many articles reported increased incidence of urinary tract infection (UTI) due to Extended-Spectrum Beta-Lactamase (ESBL)-producing E. coli. No data are available to date regarding patients presenting with complicated upper ESBL-positive E. coli UTI and sepsis. We report the clinical presentation, management, and outcomes in seven cases. MATERIALS AND

methodsThis prospective study was carried out between January 2008 and September 2011. Follow-ups varied in patients according to their disease presentation and clinical outcomes. All strains were cultured and identified by the Clinical Microbiology Laboratory and were recovered from blood and urine cultures. In-vitro presence of ESBL was confirmed with Clinical and Laboratory Standard Institute double disc method.

resultsIn the study period, 49 patients needed hospitalization for upper UTI. Overall, in 25 patients (51%), cultures were negative. In the remaining, seven patients (14.3%) presented positive blood and urine-culture for ESBL + E. coli. Of these, four were female and three were male. Their median age was 73 years (range 66-84). The median hospital stay of these patients was 23 days (range 13 to 45 days).

conclusionsThe current situation of multiple bacterial antibiotic resistance has become a worrisome issue in UTI. Multi-drug-resistant E. coli can be readily encountered in hospital settings during daily clinical practice, and urologist should act timely. The management of such infections is extremely important for the future, with particular reference to prevention of new antibiotic resistance patterns.

Indexed as

Escherichia coliExtended-spectrum beta-lactamase positivehydronephrosisinfectionpyonephrosissepsis

Identifiers

PMID24833818
PMCPMC4021646
OpenAlexW2043134671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.