Evidence map›Paper›PMID 24833687›Full record

ReviewBMJ open2014

Evidence-informed recommendations for rehabilitation with older adults living with HIV: a knowledge synthesis.

Kelly K O'Brien, Patricia Solomon, Barry Trentham, Duncan MacLachlan, Joy MacDermid, Anne-Marie Tynan, Larry Baxter, Alan Casey, William Chegwidden, Greg Robinson and 3 more

Abstract readReview
In one paragraph

Review in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  15. Using upper limb kinematics to assess cognitive deficits in people living with both HIV and stroke.IEEE ... International Conference on Rehabilitation Robotics : [proceedings] · 2017
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  18. Objective Robot-Based Measures of Cognitive and Motor Function in Patients with Stroke and HIV.Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kelly K O'BrienDepartment of Physical Therapy, University of Toronto, Toronto, Ontario, Canada School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada Canadian Working Group on HIV and Rehabilitation, Toronto, Ontario, Canada.
Patricia SolomonSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Barry TrenthamDepartment of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada.
Duncan MacLachlanAIDS Committee of Toronto, Toronto, Ontario, Canada.
Joy MacDermidSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Anne-Marie TynanSt Michael's Hospital, Toronto, Ontario, Canada.
Larry BaxterCanadian Working Group on HIV and Rehabilitation, Toronto, Ontario, Canada.
Alan CaseyFaculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
William ChegwiddenNational Hospital for Neurology and Neurosurgery, University College Hospitals NHS Foundation Trust, London, UK.
Greg RobinsonCanadian Working Group on HIV and Rehabilitation, Toronto, Ontario, Canada.
Todd TranWomen's College Hospital, Toronto, Ontario, Canada.
Janet WuSt Michael's Hospital, Toronto, Ontario, Canada.
Elisse ZackCanadian Working Group on HIV and Rehabilitation, Toronto, Ontario, Canada.

Funding

Canadian Institutes of Health Research 108046
6 · The paper itself

Abstract

objectiveOur aim was to develop evidence-informed recommendations for rehabilitation with older adults living with HIV.

designWe conducted a knowledge synthesis, combining research evidence specific to HIV, rehabilitation and ageing, with evidence on rehabilitation interventions for common comorbidities experienced by older adults with HIV.

methodsWe included highly relevant HIV-specific research addressing rehabilitation and ageing (stream A) and high-quality evidence on the effectiveness of rehabilitation interventions for common comorbidities experienced by older adults ageing with HIV (stream B). We extracted and synthesised relevant data from the evidence to draft evidence-informed recommendations for rehabilitation. Draft recommendations were refined based on people living with HIV (PLHIV) and clinician experience, values and preferences, reviewed by an interprofessional team for Grading of Recommendations Assessment, Development, and Evaluation (GRADE) (quality) rating and revision and then circulated to PLHIV and clinicians for external endorsement and final refinement. We then devised overarching recommendations to broadly guide rehabilitation with older adults living with HIV.

resultsThis synthesis yielded 8 overarching and 52 specific recommendations. Thirty-six specific recommendations were derived from 108 moderate-level or high-level research articles (meta-analyses and systematic reviews) that described the effectiveness of rehabilitation interventions for comorbidities that may be experienced by older adults with HIV. Recommendations addressed rehabilitation interventions across eight health conditions: bone and joint disorders, cancer, stroke, cardiovascular disease, mental health challenges, cognitive impairments, chronic obstructive pulmonary disease and diabetes. Sixteen specific recommendations were derived from 42 research articles specific to rehabilitation with older adults with HIV. The quality of evidence from which these recommendations were derived was either low or very low, consisting primarily of narrative reviews or descriptive studies with small sample sizes. Recommendations addressed approaches to rehabilitation assessment and interventions, and contextual factors to consider for rehabilitation with older adults living with HIV.

conclusionsThese evidence-informed recommendations provide a guide for rehabilitation with older adults living with HIV.

Indexed as

Practice Guidelines as TopicAgedEvidence-Based MedicineHIV InfectionsHumansagingevidence-informed recommendationsknowledge synthesisREHABILITATION MEDICINE

Identifiers

PMID24833687
PMCPMC4024604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.