SynthesisBMJ open2014
Behaviour change interventions to promote prescribing of generic drugs: a rapid evidence synthesis and systematic review.
Synthesis in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Deterministic and stochastic interventions in reducing drug-drug interactions in inappropriate prescribing: A systematic review.PloS one · 2026Pooled it
- Public target interventions to reduce the inappropriate use of medicines or medical procedures: a systematic review.Implementation science : IS · 2020Pooled it
- Pharmaceutical policies: effects of educational or regulatory policies targeting prescribers.The Cochrane database of systematic reviews · 2019Pooled it
- What do people really think of generic medicines? A systematic review and critical appraisal of literature on stakeholder perceptions of generic drugs.BMC medicine · 2015Pooled it
- Article
- A description of sodium valproate, lamotrigine and levetiracetam consumption in the Western Cape public sector.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Observational
- Policies and Practices Catalyzing the Use of Generic Medicines: A Systematic Search and Review.Ethiopian journal of health sciences · 2021Review
- Instant Gratification as a Method to Promote Physician Practice Guideline Adherence: A Systematic Review.Cureus · 2020Review
- Public knowledge, perception, and experience with generic medications in Saudi Arabia.Saudi medical journal · 2020Article
- Article
- Behavior change interventions and policies influencing primary healthcare professionals' practice-an overview of reviews.Implementation science : IS · 2017Review
- Quality of conduct and reporting in rapid reviews: an exploration of compliance with PRISMA and AMSTAR guidelines.Systematic reviews · 2016Review
- Availability, Price, and Affordability of Essential Medicines to Manage Noncommunicable Diseases: A National Survey From Nepal.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo summarise evidence on the effectiveness of behaviour change interventions to encourage prescribing of generic forms of prescription drugs where clinically appropriate in the UK National Health Service (NHS) and similar settings.
designSystematic review. SEARCH STRATEGY: We conducted a rapid evidence synthesis in two stages: First, we searched databases, such as the Cochrane Database of Systematic Reviews (CDSR) and Database of Abstracts of Reviews of Effects (DARE), for systematic reviews of interventions that reported outcomes related to utilisation of generic drugs. In the second stage, we searched several databases including MEDLINE and EMBASE to identify primary studies of any interventions not covered by systematic reviews. DATA EXTRACTION AND QUALITY ASSESSMENT: Data were extracted into a standardised data extraction form. Standardised quality assessment tools were used to assess study quality. Two reviewers were involved in data extraction and quality assessment.
results10 reviews were included for the initial evidence synthesis, but most were of limited usefulness to our focused review question. One review evaluated the effect of prescribing policies using financial incentives and showed an increase in generic prescribing. Thirteen primary studies of other interventions were included for the rapid review. Two studies showed an increase in percentage of overall generic prescribing with an educational intervention; two studies showed an improvement in generic prescribing rates when physicians collaborated with pharmacists, though in one study this was not statistically significant; two US studies showed improvements in generic prescribing with electronic prescribing. Five out of seven studies showed positive results with multifaceted interventions.
conclusionsThe existing evidence remains insufficient to determine which behaviour change intervention or combination of interventions is most effective due to methodological weaknesses and conflicting results. Based on the evidence, financial incentives with educational intervention and audit/feedback look promising but decision-makers should take into account the practicality and costs of the interventions before implementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.