ArticleMetabolic brain disease2014
Characterizing exposures and neurobehavioral performance in Egyptian adolescent pesticide applicators.
Article in Metabolic brain disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Effects of exposure to insecticides on sleep and neurobehavioural functioning in puberty and adolescence: a scoping review.Arhiv za higijenu rada i toksikologiju · 2025Article
- Review
- Pesticide exposure and cortical brain activation among farmworkers in Costa Rica.Neurotoxicology · 2022Article
- Evaluation of occupational pesticide exposure on Egyptian male adolescent cognitive and motor functioning.Environmental research · 2021Article
- The Health Impacts of Hazardous Chemical Exposures among Child Labourers in Low- and Middle-Income Countries.International journal of environmental research and public health · 2021Review
- Risk perception and behavior in Egyptian adolescent pesticide applicators: an intervention study.BMC public health · 2020Article
- Residential proximity to greenhouse agriculture and neurobehavioral performance in Ecuadorian children.International journal of hygiene and environmental health · 2020Article
- Thyroid hormones and neurobehavioral functions among adolescents chronically exposed to groundwater with geogenic arsenic in Bangladesh.The Science of the total environment · 2019Article
- Environmental Health Research in Africa: Important Progress and Promising Opportunities.Frontiers in genetics · 2019Review
- K-variant BCHE and pesticide exposure: Gene-environment interactions in a case-control study of Parkinson's disease in Egypt.Scientific reports · 2018Article
- Pesticide Application and Khat Chewing as Predictors of the Neurological Health Outcomes among Pesticide Applicators in a Vector Control Unit, Saudi Arabia.The international journal of occupational and environmental medicine · 2018Article
- Portable Functional Neuroimaging as an Environmental Epidemiology Tool: A How-To Guide for the Use of fNIRS in Field Studies.Environmental health perspectives · 2017Article
- The impact of repeated organophosphorus pesticide exposure on biomarkers and neurobehavioral outcomes among adolescent pesticide applicators.Journal of toxicology and environmental health. Part A · 2017Article
- Comparison of neurological health outcomes between two adolescent cohorts exposed to pesticides in Egypt.PloS one · 2017Article
- Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population.European journal of nutrition · 2016Article
- Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides.Toxicology · 2016Article
- A 10-month prospective study of organophosphorus pesticide exposure and neurobehavioral performance among adolescents in Egypt.Cortex; a journal devoted to the study of the nervous system and behavior · 2016Article
- A global perspective on the influence of environmental exposures on the nervous system.Nature · 2015Review
- Relationship between Urinary Pesticide Residue Levels and Neurotoxic Symptoms among Women on Farms in the Western Cape, South Africa.International journal of environmental research and public health · 2015Article
- Sex differences in the association between exposure to indoor particulate matter and cognitive control among children (age 6-14 years) living near coal-fired power plants.Neurotoxicology and teratologyArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Children and adolescents may have occupational exposure to pesticides. Although previous studies examining prenatal pesticide exposure have identified neurobehavioral deficits in children, there are limited studies examining the impact of occupational exposure in children. The objectives of this study are to estimate exposures to the organophosphorus pesticide, chlorpyrifos (CPF), by measuring urinary levels of 3,5,6-trichloro-2-pyridinol (TCPy), a specific CPF metabolite, and blood cholinesterase (ChE) activities and to characterize neurobehavioral performance in adolescents working as seasonal pesticide applicators and non-applicator controls. A neurobehavioral test battery, consisting of 14 tests, was used to assess a broad range of functions. Applicators performed worse than controls on the majority of tests. Principal component analysis was used to reduce the number of outcome variables and two components, focused on reasoning-short-term memory and attention-executive functioning, showed significant deficits in applicators compared to non-applicators. Elevated metabolite levels were found in the applicators compared to the non-applicators, confirming CPF exposure in the applicators. Although this study is limited by a small sample size, it provides preliminary evidence of moderate CPF exposures, decreased blood ChE in some applicators and decreased neurobehavioral performance in an adolescent working population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.