Evidence map›Paper›PMID 24833254›Full record

ReviewAnnals of biomedical engineering2014

Closed-loop brain-machine-body interfaces for noninvasive rehabilitation of movement disorders.

Frédéric D Broccard, Tim Mullen, Yu Mike Chi, David Peterson, John R Iversen, Mike Arnold, Kenneth Kreutz-Delgado, Tzyy-Ping Jung, Scott Makeig, Howard Poizner and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Review
  6. Review
  7. Article
  8. Article
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  14. Article
  15. Article
  16. Wearable EEG and beyond.Biomedical engineering letters · 2019
    Review
  17. Article
  18. Review
  19. Advances in closed-loop deep brain stimulation devices.Journal of neuroengineering and rehabilitation · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Frédéric D BroccardInstitute for Neural Computation, University of California San Diego, La Jolla, CA, 92093, USA, fbroccard@ucsd.edu.
Tim Mullen
Yu Mike Chi
David Peterson
John R Iversen
Mike Arnold
Kenneth Kreutz-Delgado
Tzyy-Ping Jung
Scott Makeig
Howard Poizner
Terrence Sejnowski
Gert Cauwenberghs
University of California, San Diego · USSalk Institute for Biological Studies · USCognionics (United States) · USLa Jolla Bioengineering Institute · US

Funding

EEGLAB: Software for Analysis of Human Brain DynamicsR01NS047293 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Arnaud Delorme, Scott Makeig · 2004 to 2026
$10.2M
Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
Howard Hughes Medical InstituteNCATS NIH HHS U54 TR001456NINDS NIH HHS NS065701NINDS NIH HHS R01 NS047293NINDS NIH HHS R01-NS047293-09A1NINDS NIH HHS U54 NS065701
6 · The paper itself

Abstract

Traditional approaches for neurological rehabilitation of patients affected with movement disorders, such as Parkinson's disease (PD), dystonia, and essential tremor (ET) consist mainly of oral medication, physical therapy, and botulinum toxin injections. Recently, the more invasive method of deep brain stimulation (DBS) showed significant improvement of the physical symptoms associated with these disorders. In the past several years, the adoption of feedback control theory helped DBS protocols to take into account the progressive and dynamic nature of these neurological movement disorders that had largely been ignored so far. As a result, a more efficient and effective management of PD cardinal symptoms has emerged. In this paper, we review closed-loop systems for rehabilitation of movement disorders, focusing on PD, for which several invasive and noninvasive methods have been developed during the last decade, reducing the complications and side effects associated with traditional rehabilitation approaches and paving the way for tailored individual therapeutics. We then present a novel, transformative, noninvasive closed-loop framework based on force neurofeedback and discuss several future developments of closed-loop systems that might bring us closer to individualized solutions for neurological rehabilitation of movement disorders.

Indexed as

AnimalsBrainFeedback, PhysiologicalHumansMovement DisordersNeuronal Plasticity

Identifiers

PMID24833254
PMCPMC4099421
OpenAlexW2024564270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.