ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2014
Exploring the relationship between EQ-5D, DLQI and PASI, and mapping EQ-5D utilities: a cross-sectional study in psoriasis from Hungary.
Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- A Systematic Review of 207 Studies Describing Validation Aspects of the Dermatology Life Quality Index.Acta dermato-venereologica · 2024Pooled it
- Biologicals and small molecules in psoriasis: A systematic review of economic evaluations.PloS one · 2018Pooled it
- Estimating health related quality of life effects in vitiligo. Mapping EQ-5D-5 L utilities from vitiligo specific scales: VNS, VitiQoL and re-pigmentation measures using data from the HI-Light trial.Health and quality of life outcomes · 2023Trial
- Improvement in Patient-Reported Outcomes (Dermatology Life Quality Index and the Psoriasis Symptoms and Signs Diary) with Guselkumab in Moderate-to-Severe Plaque Psoriasis: Results from the Phase III VOYAGE 1 and VOYAGE 2 Studies.American journal of clinical dermatology · 2019Trial
- Relationship between Dermatology Life Quality Index Scores and EQ-5D-5L Utility Values in Adults with Atopic Dermatitis: Development of a Swedish Mapping Model.Acta dermato-venereologica · 2026Article
- Mapping Dermatology Life Quality Index with EQ-5D health utility index score in Chinese patients with moderate to severe psoriasis.Journal of comparative effectiveness research · 2025Article
- Comparing EQ-5D-5L, PROPr, SF-6D and TTO utilities in patients with chronic skin diseases.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Beyond Skin Clearance: Personalized Strategies for DLQI Improvement in Psoriasis -Insights From a Shanghai Prospective Cohort.Psoriasis (Auckland, N.Z.) · 2025Article
- Impact of residual skin lesions and previous biologic treatment failure on patient-reported outcomes in patients with psoriasis receiving biologic treatment.The Journal of dermatology · 2024Observational
- Relationship Between Family History and Quality of Life in Patients with Psoriasis: A Cross-Sectional Study from China.Clinical, cosmetic and investigational dermatology · 2024Article
- Quality of life, social support, and adherence in female patients with thyroid disorders.BMC women's health · 2023Article
- Comparison of the Objective Severity and the Esthetic Perception of Nail Symptoms in Psoriasis.Skin appendage disorders · 2022Article
- Assessment of health state utilities in dermatology: an experimental time trade-off value set for the dermatology life quality index.Health and quality of life outcomes · 2022Article
- Article
- A Rasch model analysis of two interpretations of 'not relevant' responses on the Dermatology Life Quality Index (DLQI).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Toenail Psoriasis during Ustekinumab Therapy: Results and Limitations.Annals of dermatology · 2021Article
- Mapping Dermatology Life Quality Index (DLQI) scores to EQ-5D utility scores using data of patients with atopic dermatitis from the National Health and Wellness Study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Quality of Life in Patients with Morphea: A Cross-Sectional Study and a Review of the Current Literature.BioMed research international · 2020Review
- Cost-Effectiveness Analysis of Psoriasis Treatment Modalities in Malaysia.International journal of health policy and management · 2019Article
- Association between quality of life and clinical characteristics in patients with morphea.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a growing interest in policy making for using utility measures and identifying algorithms to convert disease-specific measures into utilities.
objectivesTo analyse the relationship between EQ-5D, Dermatology Life Quality Index (DLQI) and Psoriasis Area and Severity Index (PASI) in psoriasis. To transform DLQI scores, and key clinical, demographic and health service utilisation variables into utilities.
methodsA cross-sectional questionnaire survey of 200 consecutive adult patients with moderate to severe psoriasis was carried out in two Hungarian university clinics. The relationship between the outcome measures were analysed with correlations and with the known-groups method. Bivariate and multivariate regression algorithms on EQ-5D scores were formulated.
resultsThe mean age of respondents was 51 years (SD = 12.9), 68.5% were male, and 51.5% received biological therapy. Median EQ-5D, DLQI, and PASI scores were 0.73, 3.0, and 3.45, respectively. EQ-5D showed a moderate correlation with the DLQI and with the PASI (r s = -0.48 and -0.43, p < 0.05). Strong correlation was found between DLQI and PASI (r s = 0.81, p < 0.05). DLQI and PASI discriminated better among groups categorised by the localisation of the lesions than EQ-5D. Presence of psoriasis on the neck and/or décolletage was associated with the greatest health related quality of life (HRQOL) impairment. Ten variables were incorporated in a multivariate algorithm that accounted for 48.8% of EQ-5D variance (ANOVA p < 0.001).
conclusionsThis study provided the first evidence that patients with visible psoriatic lesions have significantly worse HRQOL compared to those with non-visible lesions, measured not only with DLQI but also with EQ-5D. In addition to demographic and clinical variables, our model included health service utilisation variables related to psoriasis, and explained higher proportion of EQ-5D variance than any previous findings in the literature.
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