Evidence map›Paper›PMID 24831549›Full record

ArticleMemorias do Instituto Oswaldo Cruz2014

Good agreements between self and clinician-collected specimens for the detection of human papillomavirus in Brazilian patients.

Karla Lopes Mandu de Campos, Ana Paula Machado, Flávia Gatto de Almeida, Camila Mareti Bonin, Thiago Theodoro Martins Prata, Larissa Zatorre Almeida, Cacilda Tezelli Junqueira Padovani, Alda Maria Teixeira Ferreira, Carlos Eurico Dos Santos Fernandes, Inês Aparecida Tozetti

Abstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Extended HPV Genotyping to Compare HPV Type Distribution in Self- and Provider-Collected Samples for Cervical Cancer Screening.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karla Lopes Mandu de CamposLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Ana Paula MachadoLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Flávia Gatto de AlmeidaLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Camila Mareti BoninLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Thiago Theodoro Martins PrataLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Larissa Zatorre AlmeidaLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Cacilda Tezelli Junqueira PadovaniLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Alda Maria Teixeira FerreiraLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Carlos Eurico Dos Santos FernandesLaboratório de Imunologia e Biologia Molecular de Vírus, Centro de Ciências Biológicas e da Saúde.
Inês Aparecida TozettiFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women infected with human papillomavirus (HPV) are at a higher risk of developing cervical lesions. In the current study, self and clinician-collected vaginal and cervical samples from women were processed to detect HPV DNA using polymerase chain reaction (PCR) with PGMY09/11 primers. HPV genotypes were determined using type-specific PCR. HPV DNA detection showed good concordance between self and clinician-collected samples (84.6%; kappa = 0.72). HPV infection was found in 30% women and genotyping was more concordant among high-risk HPV (HR-HPV) than low-risk HPV (HR-HPV). HPV16 was the most frequently detected among the HR-HPV types. LR-HPV was detected at a higher frequency in self-collected; however, HR-HPV types were more frequently identified in clinician-collected samples than in self-collected samples. HPV infections of multiple types were detected in 20.5% of clinician-collected samples and 15.5% of self-collected samples. In this study, we demonstrated that the HPV DNA detection rate in self-collected samples has good agreement with that of clinician-collected samples. Self-collected sampling, as a primary prevention strategy in countries with few resources, could be effective for identifying cases of HR-HPV, being more acceptable. The use of this method would enhance the coverage of screening programs for cervical cancer.

Indexed as

AdultAgedCervix UteriDNA, ViralFemaleGenotypeHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsPolymerase Chain ReactionSelf CareSensitivity and SpecificitySpecimen HandlingYoung AdultDNA, Viral

Identifiers

PMID24831549
PMCPMC4131789

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.