ArticlePLoS neglected tropical diseases2014
Projected future distributions of vectors of Trypanosoma cruzi in North America under climate change scenarios.
Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of climate change on neglected tropical diseases: a systematic review.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021Pooled it
- Phenotypic variation in populations of the mosquito vector, Aedes aegypti, and implications for predicting the effects of temperature and climate change on dengue transmission.PLoS neglected tropical diseases · 2025Article
- The patent landscape of Chagas disease vaccines indicates major underinvestment in an emerging global health threat.Nature biotechnology · 2025Article
- Potential vertical transmission of genetically diverse Trypanosoma cruzi in natural rodent populations.PLoS neglected tropical diseases · 2025Article
- Heart transplantation in South America: Risk factors, challenges, and opportunities.JHLT open · 2025Article
- Chagas Disease: Epidemiology, Diagnosis, and Treatment.Current cardiology reports · 2024Review
- Genetic Diversity ofLife (Basel, Switzerland) · 2024Review
- Chagas disease in the United States: a call for increased investment and collaborative research.Lancet regional health. Americas · 2024Review
- Structural investigation of Trypanosoma cruzi Akt-like kinase as drug target against Chagas disease.Scientific reports · 2024Article
- Climate change-induced degradation of expert range maps drawn for kissing bugs (Hemiptera: Reduviidae) and long-standing current and future sampling gaps across the Americas.Memorias do Instituto Oswaldo Cruz · 2024Article
- Article
- Climate change and the prevention of cardiovascular disease.American journal of preventive cardiology · 2022Review
- Toward New Epidemiological Landscapes ofTropical medicine and infectious disease · 2022Article
- Models of spatial analysis for vector-borne diseases studies: A systematic review.Veterinary world · 2022Article
- Worldwide Control and Management of Chagas Disease in a New Era of Globalization: a Close Look at Congenital Trypanosoma cruzi Infection.Clinical microbiology reviews · 2022Review
- The Importance of Screening for Chagas Disease Against the Backdrop of Changing Epidemiology in the USA.Current tropical medicine reports · 2022Review
- Evaluation of the Chagas Western Blot IgG Assay for the Diagnosis of Chagas Disease.Pathogens (Basel, Switzerland) · 2021Article
- Higher temperatures reduce the number of Trypanosoma cruzi parasites in the vector Triatoma pallidipennis.Parasites & vectors · 2021Article
- The effects of climate change on infectious diseases with cutaneous manifestations.International journal of women's dermatology · 2021Review
- Modelling geospatial distributions of the triatomine vectors of Trypanosoma cruzi in Latin America.PLoS neglected tropical diseases · 2020Article
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6 authors.
Funding
Abstract
backgroundChagas disease kills approximately 45 thousand people annually and affects 10 million people in Latin America and the southern United States. The parasite that causes the disease, Trypanosoma cruzi, can be transmitted by insects of the family Reduviidae, subfamily Triatominae. Any study that attempts to evaluate risk for Chagas disease must focus on the ecology and biogeography of these vectors. Expected distributional shifts of vector species due to climate change are likely to alter spatial patterns of risk of Chagas disease, presumably through northward expansion of high risk areas in North America. METHODOLOGY/PRINCIPAL
findingsWe forecast the future (2050) distributions in North America of Triatoma gerstaeckeri and T. sanguisuga, two of the most common triatomine species and important vectors of Trypanosoma cruzi in the southern United States. Our aim was to analyze how climate change might affect the future shift of Chagas disease in North America using a maximum entropy algorithm to predict changes in suitable habitat based on vector occurrence points and predictive environmental variables. Projections based on three different general circulation models (CCCMA, CSIRO, and HADCM3) and two IPCC scenarios (A2 and B2) were analyzed. Twenty models were developed for each case and evaluated via cross-validation. The final model averages result from all twenty of these models. All models had AUC >0.90, which indicates that the models are robust. Our results predict a potential northern shift in the distribution of T. gerstaeckeri and a northern and southern distributional shift of T. sanguisuga from its current range due to climate change. CONCLUSIONS/SIGNIFICANCE: The results of this study provide baseline information for monitoring the northward shift of potential risk from Chagas disease in the face of climate change.
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