ReviewClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2014
Graph theory findings in the pathophysiology of temporal lobe epilepsy.
Review in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Application of Graph Theory for Identifying Connectivity Patterns in Human Brain Networks: A Systematic Review.Frontiers in neuroscience · 2019Pooled it
- Seizure Freedom Despite Piriform Cortex Sparing: Structural Connectivity Remodeling After SEEG-Guided Mesial Temporal RFTC.European journal of neurology · 2026Article
- High-Definition Brain Network (HDBN) Delineation of CDKL5 Deficiency Disorder (CDD) in Genetically Engineered Mice.Biomolecules · 2026Article
- A complex network perspective on brain disease.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Morphometric Similarity Loss and Gray Matter Atrophy Align with Neurotransmitter and Mitochondrial Maps in Drug-Resistant Epilepsy.Neuropsychiatric disease and treatment · 2026Article
- Altered Interictal Bed Nucleus of Stria Terminalis Connectivity in Patients With Temporal Lobe Epilepsy.Neurology · 2025Article
- Brain Connectivity, Neural Networks, and Resilience in Aging and Neurodegeneration.The American journal of pathology · 2025Review
- Stronger pre-surgical functional connectivity networks are associated with improved surgical outcome in temporal lobe epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Geometric representations of brain networks can predict the surgery outcome in temporal lobe epilepsy.NPJ systems biology and applications · 2025Article
- Individualized morphological covariation network aberrance associated with seizure relapse after antiseizure medication withdrawal.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Change in Structural Connectivity Following Stereotactic Thermocoagulation in Mesial Temporal Lobe Epilepsy Patients.European journal of neurology · 2025Article
- Neurobiologically informed graph theory analysis of the language system.Network neuroscience (Cambridge, Mass.) · 2025Article
- Age-related changes in human brain functional connectivity using graph theory and machine learning techniques in resting-state fMRI data.GeroScience · 2024Article
- Article
- Delineating abnormal individual structural covariance brain network organization in pediatric epilepsy with unilateral resection of visual cortex.Epilepsy & behavior reports · 2024Article
- Hippocampal Network Dysfunction in Early Psychosis: A 2-Year Longitudinal Study.Biological psychiatry global open science · 2023Article
- Multiparametric mapping of white matter reorganizations in patients with frontal glioma-related epilepsy.CNS neuroscience & therapeutics · 2023Article
- Magnetoencephalography-based approaches to epilepsy classification.Frontiers in neuroscience · 2023Review
- The time-evolving epileptic brain network: concepts, definitions, accomplishments, perspectives.Frontiers in network physiology · 2023Review
- Alterations in brain network functional connectivity and topological properties in DRE patients.Frontiers in neurology · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Temporal lobe epilepsy (TLE) is the most common form of adult epilepsy. Accumulating evidence has shown that TLE is a disorder of abnormal epileptogenic networks, rather than focal sources. Graph theory allows for a network-based representation of TLE brain networks, and has potential to illuminate characteristics of brain topology conducive to TLE pathophysiology, including seizure initiation and spread. We review basic concepts which we believe will prove helpful in interpreting results rapidly emerging from graph theory research in TLE. In addition, we summarize the current state of graph theory findings in TLE as they pertain its pathophysiology. Several common findings have emerged from the many modalities which have been used to study TLE using graph theory, including structural MRI, diffusion tensor imaging, surface EEG, intracranial EEG, magnetoencephalography, functional MRI, cell cultures, simulated models, and mouse models, involving increased regularity of the interictal network configuration, altered local segregation and global integration of the TLE network, and network reorganization of temporal lobe and limbic structures. As different modalities provide different views of the same phenomenon, future studies integrating data from multiple modalities are needed to clarify findings and contribute to the formation of a coherent theory on the pathophysiology of TLE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.