Evidence map›Paper›PMID 24830339›Full record

Trial reportBritish journal of clinical pharmacology2014

A clinical pharmacology study of fixed vs. free combination of inhaled beclometasone dipropionate and formoterol fumarate dry powder inhalers in asthmatic adolescents.

Bo L Chawes, Mirco Govoni, Annalisa Piccinno, Eskil Kreiner-Møller, Nadja H Vissing, Li Mortensen, Erik Nilsson, Amalie Bisgaard, Maja Deleuran, Nanna Skytt and 3 more

Registry-linked trialOpen access · bronzeAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in British journal of clinical pharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01191424 (A Multicenter, Multinational, Single-Dose, Open Label, Randomized, 2-Way Crossover, Clinical Pharmacology Study of CHF 1535 100/6 Next™ DPI), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01191424 phase2completednot on this map

A Multicenter, Multinational, Single-Dose, Open Label, Randomized, 2-Way Crossover, Clinical Pharmacology Study of CHF 1535 100/6 Next™ DPI (Fixed Combination of Beclomethasone Dipropionate 100 µg Plus Formoterol 6 µg) Versus the Free Combination of Licensed Beclomethasone DPI and Formoterol DPI in Asthmatic Adolescents and Adult Patients

TypeinterventionalSponsorChiesi Farmaceutici S.p.A.Ran2010 to 2011Enrolled57ConditionsAsthmaArmsCHF1535 NEXT DPI, BDP DPI and formoterol DPI
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Bo L ChawesCopenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark.
Mirco Govoni
Annalisa Piccinno
Eskil Kreiner-Møller
Nadja H Vissing
Li Mortensen
Erik Nilsson
Amalie Bisgaard
Maja Deleuran
Nanna Skytt
Nasim Samandari
Daniela Acerbi
Hans Bisgaard
University of Copenhagen · DKGentofte Hospital · DKChiesi (France) · FRChiesi Foundation · ITCopenhagen Prospective Studies on Asthma in Childhood · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, InhalationAdolescentAnti-Asthmatic AgentsAsthmaBeclomethasoneBiological AvailabilityCross-Over StudiesDrug CombinationsDrug Therapy, CombinationDry Powder InhalersEthanolaminesFemaleFormoterol FumarateHumansMalePatient ComplianceAnti-Asthmatic AgentsBeclomethasoneDrug CombinationsEthanolaminesFormoterol Fumarate

Identifiers

PMID24830339
PMCPMC4243893
OpenAlexW2070954183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.