Evidence map›Paper›PMID 24829869›Full record

ReviewWorld journal of orthopedics2014

New perspectives for articular cartilage repair treatment through tissue engineering: A contemporary review.

Giuseppe Musumeci, Paola Castrogiovanni, Rosalia Leonardi, Francesca Maria Trovato, Marta Anna Szychlinska, Angelo Di Giunta, Carla Loreto, Sergio Castorina

Open access · greenAbstract readReview
In one paragraph

Review in World journal of orthopedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Particulate cartilage and platelet-rich plasma treatment for knee chondral defects in sheep.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Strategies for Articular Cartilage Repair and Regeneration.Frontiers in bioengineering and biotechnology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Giuseppe MusumeciGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Paola CastrogiovanniGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Rosalia LeonardiGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Francesca Maria TrovatoGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Marta Anna SzychlinskaGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Angelo Di GiuntaGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Carla LoretoGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
Sergio CastorinaGiuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy.
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper review we describe benefits and disadvantages of the established methods of cartilage regeneration that seem to have a better long-term effectiveness. We illustrated the anatomical aspect of the knee joint cartilage, the current state of cartilage tissue engineering, through mesenchymal stem cells and biomaterials, and in conclusion we provide a short overview on the rehabilitation after articular cartilage repair procedures. Adult articular cartilage has low capacity to repair itself, and thus even minor injuries may lead to progressive damage and osteoarthritic joint degeneration, resulting in significant pain and disability. Numerous efforts have been made to develop tissue-engineered grafts or patches to repair focal chondral and osteochondral defects, and to date several researchers aim to implement clinical application of cell-based therapies for cartilage repair. A literature review was conducted on PubMed, Scopus and Google Scholar using appropriate keywords, examining the current literature on the well-known tissue engineering methods for the treatment of knee osteoarthritis.

Indexed as

CartilageMesenchymal stem cellsOsteoarthritisRepairScaffoldsTissue engineering

Identifiers

PMID24829869
PMCPMC4017310
OpenAlexW2070396748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.