Evidence map›Paper›PMID 24829846›Full record

ArticleMessenger (Los Angeles, Calif. : Print)2012

Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes.

Timothy F Walseth, Yaping Lin-Moshier, Karin Weber, Jonathan S Marchant, James T Slama, Andreas H Guse

Open access · greenAbstract read
In one paragraph

Article in Messenger (Los Angeles, Calif. : Print), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Convergent activation of CaScience signaling · 2023
    Article
  5. Article
  6. TPC Functions in the Immune System.Handbook of experimental pharmacology · 2023
    Article
  7. T cell CaFrontiers in immunology · 2023
    Review
  8. NAADP-Evoked CaHandbook of experimental pharmacology · 2023
    Article
  9. NAADP-Dependent TPC Current.Handbook of experimental pharmacology · 2023
    Article
  10. Endo-Lysosomal Two-Pore Channels and Their Protein Partners.Handbook of experimental pharmacology · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. NAADP-binding proteins find their identity.Trends in biochemical sciences · 2022
    Review
  16. Article
  17. Review
  18. NAADP: From Discovery to Mechanism.Frontiers in immunology · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Timothy F WalsethDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Yaping Lin-MoshierDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Karin WeberThe Calcium Signalling Group, Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Jonathan S MarchantDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
James T SlamaDepartment of Medicinal and Biological Chemistry, University of Toledo, Toledo, OH 43614, USA.
Andreas H GuseThe Calcium Signalling Group, Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany ; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
University of Minnesota Medical Center · USUniversität Hamburg · DEUniversity of Toledo · US

Funding

Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7M
NIGMS NIH HHS R01 GM088790
6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a messenger that regulates calcium release from intracellular acidic stores. Although several channels, including two-pore channels (TPC), ryanodine receptor (RYR) and mucolipin (TRP-ML1) have been implicated in NAADP regulation of calcium signaling, the NAADP receptor has not been identified. In this study, the photoaffinity probe, [

Indexed as

[32P]5-N3-NAADPJurkat T CellsNAADPPhotoaffinity Labeling

Identifiers

PMID24829846
PMCPMC4017354
OpenAlexW2035107224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.