ReviewNeural plasticity2014
Animal models of subjective tinnitus.
Review in Neural plasticity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preclinical Experiments for Hypospadias Surgery: Systematic Review and Quality Assessment.Frontiers in pediatrics · 2021Pooled it
- Deep brain reconditioning stimulation suppresses tinnitus in a rat model.Scientific reports · 2026Article
- Challenges of using tissue engineering methods in the treatment of hypospadias.Frontiers in bioengineering and biotechnology · 2025Review
- Cortical evoked activity is modulated by the sleep state in a ferret model of tinnitus. A cross-case study.PloS one · 2024Article
- Eavesdropping on Tinnitus Using MEG: Lessons Learned and Future Perspectives.Journal of the Association for Research in Otolaryngology : JARO · 2023Review
- The Effect of Noise Trauma and Deep Brain Stimulation of the Medial Geniculate Body on Tissue Activity in the Auditory Pathway.Brain sciences · 2022Article
- Reporting Data on Auditory Brainstem Responses (ABR) in Rats: Recommendations Based on Review of Experimental Protocols and Literature.Brain sciences · 2021Article
- What's the buzz? The neuroscience and the treatment of tinnitus.Physiological reviews · 2021Review
- Quality of Reporting in Preclinical Urethral Tissue Engineering Studies: A Systematic Review to Assess Adherence to the ARRIVE Guidelines.Animals : an open access journal from MDPI · 2021Review
- Pharmacotherapy of Tinnitus.Current topics in behavioral neurosciences · 2021Review
- Pharmacological Evaluation of Drugs in Animal Models of Tinnitus.Current topics in behavioral neurosciences · 2021Review
- Auditory Brainstem Responses (ABR) of Rats during Experimentally Induced Tinnitus: Literature Review.Brain sciences · 2020Review
- Regulation of auditory plasticity during critical periods and following hearing loss.Hearing research · 2020Review
- Animal Models of Tinnitus: A Review.Otolaryngologic clinics of North America · 2020Review
- Use of the guinea pig in studies on the development and prevention of acquired sensorineural hearing loss, with an emphasis on noise.The Journal of the Acoustical Society of America · 2019Review
- Untangling the genomics of noise-induced hearing loss and tinnitus: Contributions of Mus musculus and Homo sapiens.The Journal of the Acoustical Society of America · 2019Review
- Gap-induced inhibition of the post-auricular muscle response in humans and guinea pigs.Hearing research · 2019Article
- Review
- Plasticity in Limbic Regions at Early Time Points in Experimental Models of Tinnitus.Frontiers in systems neuroscience · 2019Article
- Why Is There No Cure for Tinnitus?Frontiers in neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tinnitus is one of the major audiological diseases, affecting a significant portion of the ageing society. Despite its huge personal and presumed economic impact there are only limited therapeutic options available. The reason for this deficiency lies in the very nature of the disease as it is deeply connected to elementary plasticity of auditory processing in the central nervous system. Understanding these mechanisms is essential for developing a therapy that reverses the plastic changes underlying the pathogenesis of tinnitus. This requires experiments that address individual neurons and small networks, something usually not feasible in human patients. However, in animals such invasive experiments on the level of single neurons with high spatial and temporal resolution are possible. Therefore, animal models are a very critical element in the combined efforts for engineering new therapies. This review provides an overview over the most important features of animal models of tinnitus: which laboratory species are suitable, how to induce tinnitus, and how to characterize the perceived tinnitus by behavioral means. In particular, these aspects of tinnitus animal models are discussed in the light of transferability to the human patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.