ArticleIranian Red Crescent medical journal2014
The effect of lemon inhalation aromatherapy on nausea and vomiting of pregnancy: a double-blinded, randomized, controlled clinical trial.
Article in Iranian Red Crescent medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Pooled it
- Integrative and complementary practices to control nausea and vomiting in pregnant women: a systematic review.Revista da Escola de Enfermagem da U S P · 2022Pooled it
- Aromatherapy for treatment of postoperative nausea and vomiting.The Cochrane database of systematic reviews · 2018Pooled it
- Interventions for nausea and vomiting in early pregnancy.The Cochrane database of systematic reviews · 2015Pooled it
- The effect of lemon inhalation aromatherapy on pain, nausea, as well as vomiting and neurovascular assessment in patients for lower extremity fracture surgery: a randomized trial.BMC complementary medicine and therapies · 2023Trial
- Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol.Reproductive health · 2025Article
- Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms.Therapeutics and clinical risk management · 2025Review
- A Status Review on Health-Promoting Properties and Global Regulation of Essential Oils.Molecules (Basel, Switzerland) · 2023Review
- Assessing the safety and use of medicinal herbs during pregnancy: a cross-sectional study in São Paulo, Brazil.Frontiers in pharmacology · 2023Article
- Article
- Evaluation of the Antimicrobial Activity of Four Plant Essential Oils against Some Food and Phytopathogens Isolated from Processed Meat Products in Egypt.Foods (Basel, Switzerland) · 2022Article
- Effect of Integrated Pictorial Handbook Education and Counseling on Improving Anemia Status, Knowledge, Food Intake, and Iron Tablet Compliance Among Anemic Pregnant Women in Indonesia: A Quasi-Experimental Study.Journal of multidisciplinary healthcare · 2020Article
- Biological Activities and Safety ofInternational journal of molecular sciences · 2018Review
- Effects of Complementary Medicine on Nausea and Vomiting in Pregnancy: A Systematic Review.International journal of preventive medicine · 2018Review
- Use of lipid-lowering medicinal herbs during pregnancy: A systematic review on safety and dosage.ARYA atherosclerosis · 2017Review
- An Overview of the Biological Effects of Some Mediterranean Essential Oils on Human Health.BioMed research international · 2017Review
- The Effect of Combined Inhalation Aromatherapy with Lemon and Peppermint on Nausea and Vomiting of Pregnancy: A Double-Blind, Randomized Clinical Trial.Iranian journal of nursing and midwifery researchArticle
- Effects of red clover on hot flash and circulating hormone concentrations in menopausal women: a systematic review and meta-analysis.Avicenna journal of phytomedicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNausea and vomiting of pregnancy are amongst the most common complaints that effects on both the physical and mental conditions of the pregnant women. Due to the increasing tendency of women to use herbal medications during pregnancy, the effect of lemon inhalation aromatherapy on nausea and vomiting of pregnancy was investigated in this study.
objectivesThe aim of this study was to determine the effect of lemon inhalation aromatherapy on nausea and vomiting during pregnancy. MATERIALS AND
methodsThis was a randomized clinical trial in which 100 pregnant women with nausea and vomiting who had eligibility criteria were randomly divided into intervention and control groups based on four- and six-random block sampling method. Lemon essential oil and placebo were given to the intervention and control groups, respectively, to inhale it as soon as they felt nausea. The nausea, vomiting, and retch intensity were investigated 24 hours before and during the four days of treatment by means of PUQE-24 (24-hour Pregnancy Unique Quantification of Emesis).
resultsThere was a statistically significant difference between the two groups in the mean scores of nausea and vomiting on the second and fourth days (P = 0.017 and P = 0.039, respectively). The means of nausea and vomiting intensity in the second and fourth days in the intervention group were significantly lower than the control group. In addition, in intragroup comparison with ANOVA with repeated measures, the nausea and vomiting mean in the five intervals, showed a statistically significant difference in each group (P < 0.001 and P = 0.049, respectively).
conclusionsLemon scent can be effective in reducing nausea and vomiting of pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.