ArticleMiddle East journal of digestive diseases2013
Association between Helicobacter pylori and Serum Leptin in Iranian Dyspeptic Patients.
Article in Middle East journal of digestive diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 3 citations in OpenAlex.
- Review
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- The Possible Role ofFrontiers in microbiology · 2017Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundTo investigate any possible relationship between serum leptin level and H.pylori infection in dyspeptic Iranian adults.
methodsA total of 153 dyspeptic patients referring to Firoozgar hospital for esophagogastroduodenoscopywere enrolled in the study. Serum leptin level was measuredbefore endoscopy, after overnight fasting. Two biopsy specimens weretaken from antrum for each patient during endoscopy: one to detect H. pyloriinfection by Rapid Urease Test (RUT) and the other evaluated by an expertpathologist, blind to the RUT results and patients. Serum leptin level was comparedbetween H.pylori-positive negative groups.
resultsA total of 153 dyspeptic patients with the mean age of 43.2±14.3 years wereevaluated. The overall prevalence of H.pylori infection was 49.6%. H.pyloriinfection was significantly associated with serum leptin level (p<0.001). In addition,we found a significant relationship between serum leptin level and gender(p<0.02). Furthermore, serum leptin level was correlated with age (r=0.17,p=0.0031). However, the H.pylori-positive group was older in comparison tothe H.pylori negative group (45.65±13.9 vs. 40.7±14.13, p=0.035). The twogroups were not significantly different in terms of gender, height, weight orBMI.
conclusionH.pylori infection may influence leptin production. Advanced age might exposethe individual to H.pylori infection and consequently influence the leptinlevel.
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Identifiers
24829687PMC3990176W2137821148What OpenQuestion holds
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