Evidence map›Paper›PMID 24829615›Full record

ReviewJournal of ovarian research2014

Fertility drugs, reproductive strategies and ovarian cancer risk.

Federica Tomao, Giuseppe Lo Russo, Gian Paolo Spinelli, Valeria Stati, Alessandra Anna Prete, Natalie Prinzi, Marsela Sinjari, Patrizia Vici, Anselmo Papa, Maria Stefania Chiotti and 2 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of ovarian research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Medicines (Basel, Switzerland) · 2018
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. GnRH evokes localized subplasmalemmal calcium signaling in gonadotropes.Molecular endocrinology (Baltimore, Md.) · 2014
    Article
  9. Article
  10. Correlation between fertility drugs use and malignant melanoma incidence: the state of the art.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Federica TomaoDepartment of Gynaecological and Obstetrical Sciences and Urological Sciences, University of Rome "Sapienza" Viale Regina Elena 324, 00161 Rome, Italy.
Giuseppe Lo RussoDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Gian Paolo SpinelliDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Valeria StatiDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Alessandra Anna PreteDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Natalie PrinziDepartment of Experimental Medicine, University of Rome "Sapienza", Viale Regina Elena 324, 00161 Rome, Italy.
Marsela SinjariDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Patrizia ViciDepartment of Medical Oncology, National Cancer Institute of Rome, Italy, Rome.
Anselmo PapaDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Maria Stefania ChiottiDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Pierluigi Benedetti PaniciDepartment of Gynaecological and Obstetrical Sciences and Urological Sciences, University of Rome "Sapienza" Viale Regina Elena 324, 00161 Rome, Italy.
Silverio TomaoDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "Sapienza," Corso della Repubblica, 04100 Latina, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several adverse effects have been related to infertility treatments, such as cancer development. In particular, the relationship between infertility, reproductive strategies, and risk of gynecological cancers has aroused much interest in recent years. The evaluation of cancer risk among women treated for infertility is very complex, mainly because of many factors that can contribute to occurrence of cancer in these patients (including parity status). This article addresses the possible association between the use of fertility treatments and the risk of ovarian cancer, through a scrupulous search of the literature published thus far in this field. Our principal objective was to give more conclusive answers on the question whether the use of fertility drug significantly increases ovarian cancer risk. Our analysis focused on the different types of drugs and different treatment schedules used. This study provides additional insights regarding the long-term relationships between fertility drugs and risk of ovarian cancer.

Indexed as

ClomipheneFemaleFertility Agents, FemaleFertilization in VitroHumansInfertility, FemaleOvarian NeoplasmsRisk FactorsClomipheneFertility Agents, FemaleClomiphene citrateFertility drugsin vitro fertilizationOvarian cancerOvarian stimulation

Identifiers

PMID24829615
PMCPMC4020377
OpenAlexW2136092345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.