Evidence map›Paper›PMID 24829543›Full record

ArticleGastroenterology & hepatology2014

Irritable bowel syndrome: the role of food in pathogenesis and management.

Paula A Hayes, Marianne H Fraher, Eamonn M M Quigley

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Gastroenterology & hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it, 158 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
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  10. Trial
  11. Low-FODMAPWorld journal of gastroenterology · 2018
    Trial
  12. Review
  13. Observational
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Nutraceuticals and biotics in pediatric gastrointestinal disorders.European journal of clinical nutrition · 2024
    Review
  20. Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Paula A HayesMs Hayes is a research dietitian and Dr Fraher is a research fellow at the Alimentary Pharmabiotic Centre at the University College Cork in Cork, Ireland. Dr Quigley is a professor of medicine and human physiology at the University College Cork and chief of the Division of Gastroenterology and Hepatology at Houston Methodist Hospital and Weill Cornell Medical College in Houston, Texas.
Marianne H FraherMs Hayes is a research dietitian and Dr Fraher is a research fellow at the Alimentary Pharmabiotic Centre at the University College Cork in Cork, Ireland. Dr Quigley is a professor of medicine and human physiology at the University College Cork and chief of the Division of Gastroenterology and Hepatology at Houston Methodist Hospital and Weill Cornell Medical College in Houston, Texas.
Eamonn M M QuigleyMs Hayes is a research dietitian and Dr Fraher is a research fellow at the Alimentary Pharmabiotic Centre at the University College Cork in Cork, Ireland. Dr Quigley is a professor of medicine and human physiology at the University College Cork and chief of the Division of Gastroenterology and Hepatology at Houston Methodist Hospital and Weill Cornell Medical College in Houston, Texas.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder that affects approximately 10% to 20% of the general adult population in Europe and the Americas and is characterized by abdominal pain and altered bowel habits in the absence of reliable biomarkers. The pathophysiology of IBS is poorly understood and is currently thought to represent a complex interplay among the gut microbiota, low-grade inflammation, impaired mucosal barrier function, visceral hypersensitivity, gut motility, and alterations in the gut-brain axis. In any individual patient, 1 or more of these factors may interact to generate symptoms. Although up to 50% of patients report postprandial exacerbation of symptoms, few studies have critically assessed the role of diet in IBS. Furthermore, although many patients with IBS adopt any one of a host of dietary changes in an attempt to alleviate their symptoms, there has been, up until recently little scientific basis for any dietary recommendation in IBS. This review discusses the contribution of diet to the pathophysiology and symptoms of IBS.

Indexed as

dietFODMAPsfood allergyfood intoleranceglutengut hormonesIrritable bowel syndrome

Identifiers

PMID24829543
PMCPMC4014048
OpenAlexW17233875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.