ArticleJournal of clinical microbiology2014
Extremes of age are associated with indeterminate QuantiFERON-TB gold assay results.
Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors for Indeterminate Interferon-Gamma Release Assay for the Diagnosis of Tuberculosis in Children-A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2019Pooled it
- Trial
- Diagnostic utility of quantitative interferon-gamma release assays in elderly patients with tuberculosis.Microbiology spectrum · 2026Article
- Positivity rate of QuantiFERON-TB Gold PlusSAGE open medicine · 2026Article
- Performance of whole blood interferon-γ release assays in SARS-CoV-2 and tuberculosis is age dependent.Infection · 2025Article
- Prevalence and Risk Factors of Latent Tuberculosis Infection Detected by IGRA in Patients with Immune-Mediated Inflammatory Diseases Before and During Biologic DMARD Therapy (TITAN Study).Journal of clinical medicine · 2025Article
- Factors associated with indeterminate QuantiFERON-TB Gold Plus Test results during the COVID-19 pandemic.PloS one · 2025Article
- A regression predictive model for QuantiFERON-TB Gold PlusSAGE open medicine · 2024Article
- Article
- Tuberculosis Infection in Children and Adolescents.Pathogens (Basel, Switzerland) · 2022Review
- Host, technical, and environmental factors affecting QuantiFERON-TB Gold In-Tube performance in children below 5 years of age.Scientific reports · 2022Article
- Integrating interferon-gamma release assay testing into provision of tuberculosis preventive therapy is feasible in a tuberculosis high burden resource-limited setting: A mixed methods study.PLOS global public health · 2022Article
- Beyond QuantiFERON-TB Results, the Added Value of a Weak Mitogen Response.Frontiers in medicine · 2022Article
- Tuberculosis in the Elderly.Journal of clinical medicine · 2021Review
- Preventing tuberculosis in paediatric kidney transplant recipients: is there a role for BCG immunisation pre-transplantation in low tuberculosis incidence countries?Pediatric nephrology (Berlin, Germany) · 2021Review
- Interferon gamma release assays for detection of latent Mycobacterium tuberculosis in older Hispanic people.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Article
- Retrospective Performance Analyses of over Two Million U.S. QuantiFERON Blood Sample Results.Microbiology spectrum · 2021Article
- Low-dose steroids are associated with indeterminate QuantiFERON-TB Gold In-Tube assay results in immunocompetent children.Scientific reports · 2021Article
- Management of childhood and adolescent latent tuberculous infection (LTBI) in Germany, Austria and Switzerland.PloS one · 2021Article
- Performance of immune-based and microbiological tests in children with tuberculosis meningitis in Europe: a multicentre Paediatric Tuberculosis Network European Trials Group (ptbnet) study.The European respiratory journal · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Results from 3,263 QuantiFERON-TB Gold in-tube (QFT-GIT) assays were analyzed to determine the impact of age on test performance. The proportion of indeterminate results was significantly higher in pediatric and elderly (9.1% and 7.4%, respectively) than in adult (2.6%; chi-square test, P < 0.0001) patients. A detailed analysis of indeterminate QFT-GIT assay results is presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.