ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2014
School-located influenza vaccination decreases laboratory-confirmed influenza and improves school attendance.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Pooled it
- Herd effect from influenza vaccination in non-healthcare settings: a systematic review of randomised controlled trials and observational studies.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2016Pooled it
- Practice- and Community-Based Interventions to Increase Human Papillomavirus Vaccine Coverage: A Systematic Review.JAMA pediatrics · 2015Pooled it
- Effectiveness of Multifaceted Strategies to Increase Influenza Vaccination Uptake: A Cluster Randomized Trial.JAMA network open · 2024Trial
- Cost effectiveness of school-located influenza vaccination programs for elementary and secondary school children.BMC health services research · 2019Trial
- Cost effectiveness analysis of Year 2 of an elementary school-located influenza vaccination program-Results from a randomized controlled trial.BMC health services research · 2015Trial
- Implementation of Multifaceted Enhanced School-located Influenza Vaccination Strategies in China: A Mixed Methods Evaluation Using the RE-AIM Framework and Normalization Process Theory.International journal of behavioral medicine · 2026Article
- Insights Into monoclonal antibodies and vaccines targeting respiratory viruses.Frontiers in pediatrics · 2026Review
- Increasing child vaccination coverage can reduce influenza cases across age groups: An agent-based modeling study.The Journal of infection · 2025Article
- Parents and teachers' perspectives on a school-located influenza vaccination program: A pilot study in the Region of Murcia, Spain.Human vaccines & immunotherapeutics · 2024Article
- Exploring the pathway toward the reduction of paediatric seasonal influenza burden: school-based vaccination and surveillance.Journal of preventive medicine and hygiene · 2024Article
- Digital Gamification Tool (Let's Control Flu) to Increase Vaccination Coverage Rates: Proposal for Algorithm Development.JMIR research protocols · 2024Article
- Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study.BMJ public health · 2024Article
- The Attitudes of Healthcare Professionals in an Autonomous Community in Spain towards Paediatric Influenza Vaccination.Vaccines · 2024Article
- Analysis of factors influencing influenza outbreaks in schools in Taicang City, China.Frontiers in public health · 2024Article
- Identifying implementation strategies to address barriers of implementing a school-located influenza vaccination program in Beijing.Implementation science communications · 2023Article
- Preschool-located influenza vaccination and influenza-like illness surveillance: an Italian pilot experience.Italian journal of pediatrics · 2023Article
- Severe acute respiratory illness surveillance for influenza in Kenya: Patient characteristics and lessons learnt.Influenza and other respiratory viruses · 2022Article
- A Hemagglutinin Stem Vaccine Designed Rationally by AlphaFold2 Confers Broad Protection against Influenza B Infection.Viruses · 2022Article
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9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSchool-located influenza vaccination (SLV) programs can efficiently immunize large numbers of school-aged children. We evaluated the impact of SLV on laboratory-confirmed influenza and absenteeism.
methodsActive surveillance for influenza-like illness (ILI) was conducted on 4455 children in 4 SLV intervention and 4 control elementary schools (grades K-6) matched for sociodemographic characteristics during the 2010-2011 influenza season in Los Angeles County, California. Combined nose/throat swabs were collected from febrile children with ILI at presentation to the school nurse or during absenteeism.
resultsIn SLV schools, 26.9%-46.6% of enrolled students received at least 1 dose of either inactivated or live attenuated influenza vaccine compared with 0.8%-4.3% in control schools. Polymerase chain reaction for respiratory viruses (PCR) was performed on 1021 specimens obtained from 898 children. Specimens were positive for influenza in 217 (21.3%), including 2009 H1N1 (30.9%), H3 (9.2%), and B (59.9%). Children attending SLV schools, regardless of vaccination status, were 30.8% (95% confidence interval, 10.1%-46.8%) less likely to acquire influenza compared with children at control schools. Unvaccinated children were indirectly protected in the school with nearly 50% vaccination coverage compared with control schools (influenza rate, 27.1 vs 60.0 per 1000 children; P = .023). Unvaccinated children missed more school days than vaccinated children (4.3 vs 2.8 days per 100 school days; P < .001).
conclusionsVaccination of at least a quarter of the school population resulted in decreased influenza rates and improved school attendance. Herd immunity for unvaccinated children may occur in schools with vaccination coverage approaching 50%.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.