Evidence map›Paper›PMID 24829003›Full record

GuidelineCanadian family physician Medecin de famille canadien2014

Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia: recommendations for family physicians.

Ainsley Moore, Christopher Patterson, Linda Lee, Isabelle Vedel, Howard Bergman, Canadian Consensus Conference on the Diagnosis and Treatment of Dementia

Open access · greenAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Canadian family physician Medecin de famille canadien, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
    Pooled it
  3. Guideline
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  6. Article
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  8. Quality indicator framework for primary care of patients with dementia.Canadian family physician Medecin de famille canadien · 2022
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  14. Canadian family physician Medecin de famille canadien · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ainsley MooreAssociate Professor in the Department of Family Medicine at McMaster University in Hamilton, Ont. amoore@mcmaster.ca.
Christopher PattersonProfessor in the Division of Geriatric Medicine of the Department of Medicine at McMaster University.
Linda LeeAssociate Clinical Professor in the Department of Family Medicine at McMaster University.
Isabelle VedelAssistant Professor in the Division of Geriatrics of the Department of Family Medicine at McGill University in Montreal, Que.
Howard BergmanChair of the Department of Family Medicine, Professor of Family Medicine in the Department of Medicine and Oncology, and Dr Joseph Kaufmann Professor of Geriatric Medicine at McGill University.
Canadian Consensus Conference on the Diagnosis and Treatment of Dementia
McMaster University · CAMcGill University · CAMcGill University Health Centre · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

objectiveTo revise diagnostic strategies for Alzheimer disease (AD), update recommendations on symptomatic treatment of dementia, and provide an approach to rapidly progressive and early-onset dementias. COMPOSITION OF THE COMMITTEE: Experts and delegates representing relevant disciplines from diverse regions across Canada discussed and agreed upon revisions to the 2006 guidelines.

methodsThe GRADE (grading of recommendations, assessment, development, and evaluation) system was used to evaluate consensus on recommendations, which was defined as when 80% or more of participants voted for the recommendation. Evidence grades are reported where possible. REPORT: Important for FPs, despite advances in liquid biomarkers and neuroimaging, the diagnosis of dementia in Canada remains fundamentally clinical. New core clinical criteria for the diagnosis of AD now recognize less common, non-amnestic forms. Early-onset dementia, a rare but important condition, should prompt referral to specialists with access to genetic counselors. Rapidly progressive dementia, poorly defined in the literature, is described to facilitate detection of this rare but important condition. There are new expanded indications for cholinesterase inhibitors beyond AD, as well as guidelines for their discontinuation, which had not been previously described. New evidence regarding use of memantine, antidepressants, and other psychotropic medications in dementia care is presented.

conclusionSeveral recommendations from the Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia are relevant to FPs. For guidelines to remain useful, family physicians should participate in all stages of the ongoing development process, including topic selection.

Indexed as

Alzheimer DiseaseCanadaDementiaFamily PracticeHumans

Identifiers

PMID24829003
PMCPMC4020644
OpenAlexW2110966496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.