ArticleInfluenza and other respiratory viruses2014
Effectiveness of seasonal influenza vaccinations against laboratory-confirmed influenza-associated infections among Singapore military personnel in 2010-2013.
Article in Influenza and other respiratory viruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- The Use of Test-negative Controls to Monitor Vaccine Effectiveness: A Systematic Review of Methodology.Epidemiology (Cambridge, Mass.) · 2020Pooled it
- Seasonal influenza vaccine policy, use and effectiveness in the tropics and subtropics - a systematic literature review.Influenza and other respiratory viruses · 2016Pooled it
- Potential of the test-negative design for measuring influenza vaccine effectiveness: a systematic review.Expert review of vaccines · 2014Pooled it
- Effectiveness of inactivated influenza vaccine against laboratory-confirmed influenza among Chinese elderly: a test-negative design.BMC geriatrics · 2024Article
- Review
- Article
- Evidence for Cross-Protection Against Subsequent Febrile Respiratory Illness Episodes From Prior Infections by Different Viruses Among Singapore Military Recruits 2009-2014.The Journal of infectious diseases · 2019Article
- Epidemiologic analysis of respiratory viral infections among Singapore military servicemen in 2016.BMC infectious diseases · 2018Article
- Individual and Population Trajectories of Influenza Antibody Titers Over Multiple Seasons in a Tropical Country.American journal of epidemiology · 2018Article
- Phylogenetic relationships of the HA and NA genes between vaccine and seasonal influenza A(H3N2) strains in Korea.PloS one · 2017Article
- Risk factors for febrile respiratory illness and mono-viral infections in a semi-closed military environment: a case-control study.BMC infectious diseases · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLimited information is available about seasonal influenza vaccine effectiveness (VE) in tropical communities.
objectivesVirus subtype-specific VE was determined for all military service personnel in the recruit camp and three other non-recruit camp in Singapore's Armed Forces from 1 June 2009 to 30 June 2012.
methodsConsenting servicemen underwent nasal washes, which were tested with RT-PCR and subtyped. The test positive case and test negative control design was used to estimate the VE. To estimate the overall effect of the programme on new recruits, we used an ecological time series approach.
resultsA total of 7016 consultations were collected. The crude estimates for the VE of the triavalent vaccine against both influenza A(H1N1)pdm09 and influenza B were 84% (95% CI 78-88%, 79-86%, respectively). Vaccine efficacy against influenza A(H3N2) was markedly lower (VE 33%, 95% CI -4% to 57%). An estimated 70% (RR = 0.30; 95% CI 0.11-0.84), 39% (RR = 0.61;0.25-1.43) and 75% (RR = 0.25; 95% CI 0.11-0.50) reduction in the risk of influenza A(H1N1)pdm09, influenza A(H3N2) and influenza B infections, respectively, in the recruit camp during the post-vaccination period compared with during the pre-vaccination period was observed.
conclusionsOverall, the blanket influenza vaccine programme in Singapore's Armed Forces has had a moderate to high degree of protection against influenza A(H1N1)pdm09 and influenza B, but not against influenza A(H3N2). Blanket influenza vaccination is recommended for all military personnel.
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