ArticlePloS one2014
Barriers and facilitators of adherence to antiretroviral drug therapy and retention in care among adult HIV-positive patients: a qualitative study from Ethiopia.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 8 of them syntheses that pooled it.
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Who cites it
127 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- Behavioral Theories and Motivational Features Underlying eHealth Interventions for Adolescent Antiretroviral Adherence: Systematic Review.JMIR mHealth and uHealth · 2021Pooled it
- HIV patients retention and attrition in care and their determinants in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2020Pooled it
- Systematic review on HIV situation in Addis Ababa, Ethiopia.BMC public health · 2019Pooled it
- Being HIV positive and staying on antiretroviral therapy in Africa: A qualitative systematic review and theoretical model.PloS one · 2019Pooled it
- Enhancing Public Health HIV Interventions: A Qualitative Meta-Synthesis and Systematic Review of Studies to Improve Linkage to Care, Adherence, and Retention.EBioMedicine · 2017Pooled it
- The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis.AIDS and behavior · 2017Pooled it
- Acceptability and Preferences of Two Different Community Models of ART Delivery in a High Prevalence Urban Setting in Zambia: Cluster-Randomized Trial, Nested in the HPTN 071 (PopART) Study.AIDS and behavior · 2022Trial
- Trial
- Factors associated with loss-to-follow-up of HIV-positive mothers and their infants enrolled in HIV care clinic: A qualitative study.BMC public health · 2020Trial
- "We Are Now Free to Speak": Qualitative Evaluation of an Education and Empowerment Training for HIV Patients in Namibia.PloS one · 2016Trial
- Self-Reported Side Effects and Adherence to Antiretroviral Therapy in HIV-Infected Pregnant Women under Option B+: A Prospective Study.PloS one · 2016Trial
- Trends, magnitude and determinants of viral load suppression among HIV patients on highly active anti-retroviral therapy in Tigray region, Ethiopia: a retrospective study (2016-2024).BMC infectious diseases · 2026Article
- Clinical impact and cost-effectiveness of rapid versus non-rapid antiretroviral therapy initiation in HIV-positive men who have sex with men in China using modelling and 96-week multicenter cohort data.Scientific reports · 2026Article
- Factors associated with antiretroviral therapy adherence among adolescents living with HIV in Addis Ababa, Ethiopia: structural equation modeling.AIDS research and therapy · 2026Article
- Retention and predictors of loss-to-follow-up among patients on antiretroviral therapy in the Test-and-Treat Era: evidence from a retrospective cohort study in Maputo, Mozambique.BMC infectious diseases · 2026Article
- A cross-sectional study of viral load suppression among youth living with HIV in Namibia.Southern African journal of HIV medicine · 2026Article
- Applying convergent parallel mixed methods design to investigate medication adherence among people living with HIV in resource-limited settings: methodological insights from Ghana.Frontiers in public health · 2026Article
- Challenges and Enablers of Antiretroviral Therapy Adherence Among Ethiopian Adolescents: A Qualitative Study.International journal of sexual health : official journal of the World Association for Sexual Health · 2026Article
67 more citing papers are in PubMed but not listed here.
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6 authors.
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Abstract
backgroundAntiretroviral therapy (ART) has been life saving for hundreds of thousands of Ethiopians. With increased availability of ART in recent years, achievement of optimal adherence and patient retention are becoming the greatest challenges in the management of HIV/AIDS in Ethiopia. However, few studies have explored factors influencing medication adherence to ART and retention in follow-up care among adult Ethiopian HIV-positive patients, especially in the Amhara region of the country, where almost one-third of the country's ART is prescribed. The aim of this qualitative study was to collect such data from patients and healthcare providers in the Amhara region of Ethiopia.
methodsSemi-structured interviews were conducted with 24 patients, of whom 11 had been lost to follow-up and were non-persistent with ART. In addition, focus group discussions were performed with 15 ART nurses and 19 case managers. All interviews and focus groups were audio-recorded, transcribed, and coded for themes and patterns in Amharic using a grounded theory approach. The emergent concepts and categories were translated into English.
resultsEconomic constraints, perceived stigma and discrimination, fasting, holy water, medication side effects, and dissatisfaction with healthcare services were major reasons for patients being non-adherent and lost to follow-up. Disclosure of HIV status, social support, use of reminder aids, responsibility for raising children, improved health on ART, and receiving education and counseling emerged as facilitators of adherence to ART.
conclusionsImproving adherence and retention requires integration of enhanced treatment access with improved job and food security. Healthcare providers need to be supported to better equip patients to cope with the issues associated with ART. Development of social policies and cooperation between various agencies are required to facilitate optimal adherence to ART, patient retention, and improved patient outcomes.
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