Evidence map›Paper›PMID 24828265›Full record

ReviewChemical communications (Cambridge, England)2014

Dimeric pyrrole-imidazole alkaloids: synthetic approaches and biosynthetic hypotheses.

Xiao Wang, Zhiqiang Ma, Xiaolei Wang, Saptarshi De, Yuyong Ma, Chuo Chen

Abstract readReview
In one paragraph

Review in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Total Syntheses of Agelamadin F and (±)-Tauroacidin A, Enabled by NaClOChemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Marine Pyrrole Alkaloids.Marine drugs · 2021
    Review
  7. Review
  8. Total Synthesis of (±)-Sceptrin.Organic letters · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Natural products as inspiration for the development of new synthetic methods.Journal of the Chinese Chemical Society. Zhongguo hua xue hui (Taipei, Taiwan) · 2018
    Article
  17. Article
  18. Article
  19. Asymmetric Synthesis of Axinellamines A and B.Angewandte Chemie (International ed. in English) · 2016
    Article
  20. Total synthesis of palau'amine.Nature communications · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiao WangDivision of Chemistry, Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA. Chuo.Chen@UTSouthwestern.edu.
Zhiqiang Ma
Xiaolei Wang
Saptarshi De
Yuyong Ma
Chuo Chen

Funding

Asymmetric Synthesis of Biologically Active Marine Natural ProductsR01GM079554 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHEN, CHUO · 2007 to 2016
$2.9M
NIGMS NIH HHS R01 GM079554NIGMS NIH HHS R01-GM079554
6 · The paper itself

Abstract

The pyrrole-imidazole alkaloids are a group of structurally unique and biologically interesting marine sponge metabolites. Among them, the cyclic dimers have caught synthetic chemists' attention particularly. Numerous synthetic strategies have been developed and various biosynthetic hypotheses have been proposed for these fascinating natural products. We discuss herein the synthetic approaches and the biosynthetic insights obtained from these studies.

Indexed as

AlkaloidsAnimalsBiological ProductsImidazolesPoriferaPyrrolesAlkaloidsBiological ProductsImidazolesPyrroles

Identifiers

PMID24828265
PMCPMC4096073

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.