ReviewCurrent cardiology reviews2014
Fragmented ECG as a risk marker in cardiovascular diseases.
Review in Current cardiology reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Pooled it
- Fragmented QRS as a Marker of Myocardial Fibrosis in Hypertension: a Systematic Review.Current hypertension reports · 2019Pooled it
- Use of fragmented QRS in prognosticating clinical deterioration and mortality in pulmonary embolism: A meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Pooled it
- Risk assessment of cardiac arrhythmias in the early post-COVID-19 period in non-hospitalized patients-long-term data from the PoLoCOV-CVD study.Scientific reports · 2026Observational
- Unmasking silent cardiometabolic risk: the role of fragmented QRS in obese young adults.BMC cardiovascular disorders · 2026Article
- Sudden cardiac death in stable coronary artery disease: A literature review.American heart journal plus : cardiology research and practice · 2026Review
- Article
- Beyond the type 1 pattern: comprehensive risk stratification in Brugada syndrome.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Review
- Diagnostic performance of the fragmented QRS complex on electrocardiogram for detecting myocardial scars assessed by 3.0 Tesla cardiac magnetic resonance imaging.Heart rhythm O2 · 2025Article
- Late-phase depolarization and repolarization abnormalities in english bulldogs with phenotypic expression of arrhythmogenic cardiomyopathy.Veterinary research communications · 2025Article
- Assessment of the fragmented QRS relative frequency and its predictive value in patients with pulmonary embolism.Caspian journal of internal medicine · 2025Article
- ECG Semantic Integrator (ESI): A Foundation ECG Model Pretrained with LLM-Enhanced Cardiological Text.Transactions on machine learning research · 2024Article
- Beating the heart failure odds: long-term survival after myocardial ischemia in juvenile rainbow trout.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- Association between uterine leiomyoma and fragmented QRS waves: a prospective case-control study.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Article
- QRS fragmentation versus QRS prolongation in predicting right ventricular enlargement and dysfunction in children and adults with repaired Tetralogy of Fallot.International journal of cardiology. Congenital heart disease · 2023Article
- Ventricular Arrhythmia in Cancer Patients: Mechanisms, Treatment Strategies and Future Avenues.Arrhythmia & electrophysiology review · 2023Review
- Electrical storm in hypertrophic cardiomyopathy: Cardiac magnetic resonance and sudden cardiac death risk stratification: a case report.European heart journal. Case reports · 2023Article
- Relationship between Fragmented QRS and Microvascular Dysfunction in Masked Hypertension.Pulse (Basel, Switzerland) · 2022Article
- Highlights in the association of fragmented QRS with myocardial fibrosis.Turkish journal of medical sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Various noninvasive tests for risk stratification of sudden cardiac death (SCD) were studied, mostly in the context of structural heart disease such as coronary artery disease (CAD), cardiomyopathy and heart failure but have low positive predictive value for SCD. Fragmented QRS complexes (fQRS) on a 12-lead ECG is a marker of depolarization abnormality. fQRS include presence of various morphologies of the QRS wave with or without a Q wave and includes the presence of an additional R wave (R') or notching in the nadir of the R' (fragmentation) in two contiguous leads, corresponding to a major coronary artery territory. fQRS represents conduction delay from inhomogeneous activation of the ventricles due to myocardial scar. It has a high predictive value for myocardial scar and mortality in patients CAD. fQRS also predicts arrhythmic events and mortality in patients with implantable cardioverter defibrillator. It also signifies poor prognosis in patients with nonischemic cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy and Brugada syndrome. However, fQRS is a nonspecific finding and its diagnostic prognostic should only be interpreted in the presence of pertinent clinical evidence and type of myocardial involvement (structural vs. structurally normal heart).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.