Evidence map›Paper›PMID 24827621›Full record

ArticleGut and liver2014

Recent chemotherapy reduces the maximum-standardized uptake value of 18F-fluoro-deoxyglucose positron emission tomography in colorectal cancer.

Minjong Lee, Tae Sung Yeum, Ji Won Kim, Sohee Oh, Shin Ae Lee, Hong Ran Moon, Young Hoon Choi, Yoo Min Han, Ji Min Choi, Dong Kee Jang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut and liver, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Minjong LeeDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Tae Sung YeumDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Ji Won KimDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea, Departments of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Sohee OhDepartments of Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
Shin Ae LeeDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Hong Ran MoonDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Young Hoon ChoiDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Yoo Min HanDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Ji Min ChoiDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Dong Kee JangDepartment of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Korea.
Seoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe aim of this study was to evaluate the influence of recent chemotherapy on the patterns of the maximum-standardized uptake value (M-SUV) and sensitivity of (18)F-fluoro-deoxyglucose positron emission tomography/computed tomography ((18)F-FDG-PET/CT) in colorectal cancer.

methodsWe retrospectively analyzed the FDG-PET/CT of 509 patients who underwent surgery for colorectal cancer. Subgroup analysis was performed according to chemotherapy status; 401 patients were not treated with chemotherapy and 108 patients were treated with chemotherapy within 6 months prior to surgery. Pathologic analysis of the surgical specimen was used as the gold standard.

resultsThe M-SUV was significantly lower in patients treated with chemotherapy than in those not treated with chemotherapy in pathologically confirmed same stages of disease. The difference in the sensitivity of the M-SUV according to chemotherapy status was greatest using a cutoff M-SUV value of 6.4 (p<0.001). The longest diameter of the primary tumor was the most important factor that correlated with M-SUV of the primary tumor irrespective of the chemotherapy effect (p<0.001). The M-SUV of the primary tumor was not an independent predictor of lymph node metastasis in colorectal cancer.

conclusionsThe results indicate that the M-SUV of FDG-PET/CT should be interpreted in the context of concurrent chemotherapy.

Indexed as

AgedAntineoplastic AgentsChemoradiotherapy, AdjuvantChemotherapy, AdjuvantColorectal NeoplasmsFemaleFluorodeoxyglucose F18HumansMaleNeoplasm InvasivenessNeoplasm MetastasisPositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesAntineoplastic AgentsFluorodeoxyglucose F18RadiopharmaceuticalsColorectal neoplasmsDrug therapyFDG-PET/CT

Identifiers

PMID24827621
PMCPMC4026642
OpenAlexW2027361797

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.