ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2014
Hair loss and hypothalamic-pituitary-adrenocortical axis activity in captive rhesus macaques (Macaca mulatta).
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Pooled it
- Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss.Journal of clinical medicine · 2023Review
- Effect of Pregnancy and Age on Alopecia in Adult Female Baboons (Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Association between stress and bilateral symmetrical alopecia in free-ranging Formosan macaques in Mt. Longevity, Taiwan.Scientific reports · 2021Article
- Hair cortisol in captive corral-housed baboons.General and comparative endocrinology · 2021Article
- Chimpanzees' (PeerJ · 2020Article
- Article
- Alopecia in rhesus macaques (Macaca mulatta): Association with pregnancy and chronic stress.Journal of medical primatology · 2019Article
- Hair Cortisol in Sheltered Cows and Its Association with Other Welfare Indicators.Animals : an open access journal from MDPI · 2019Article
- Social hair pulling in captive rhesus macaques (Macaca mulatta).American journal of primatology · 2017Article
- 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells.Yonsei medical journal · 2017Article
- Fatty acid supplements improve hair coat condition in rhesus macaques.Journal of medical primatology · 2017Article
- A longitudinal study of hair cortisol concentrations in Macaca nemestrina mothers and infants.American journal of primatology · 2017Article
- The correlation between alopecia and temperament in rhesus macaques (Macaca mulatta) at four primate facilities.American journal of primatology · 2017Article
- Prior facility affects alopecia in adulthood for rhesus macaques.American journal of primatology · 2017Article
- Assessing significant (>30%) alopecia as a possible biomarker for stress in captive rhesus monkeys (Macaca mulatta).American journal of primatology · 2017Article
- Factors influencing alopecia and hair cortisol in rhesus macaques (Macaca mulatta).Journal of medical primatology · 2016Article
- Alopecia in Outdoor Group- and Corral-Housed Baboons (Papio hamadryas spp.).Journal of the American Association for Laboratory Animal Science : JAALAS · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Hair loss is a common problem in captive macaque colonies. A potential factor is the possible influence of stressful environments in the development of hair loss. We examined the relationship between hair loss and chronic hypothalamic-pituitary-adrenal (HPA) axis activity by measuring cortisol in hair. Adult male and female rhesus macaques housed at 3 primate facilities in the United States were screened for degree of hair loss and observed for evidence of hair-plucking behavior. Hair samples and photographic data were obtained from 99 subjects, none of which were hair-pluckers. Macaques with greater than 30% hair loss (alopecia group) showed higher concentrations of hair cortisol than did those with less than 5% hair loss (control group), a finding that was unrelated to age, body weight, or the month in which the sample was collected. Hair loss scores were positively correlated with hair cortisol levels across all monkeys and within the alopecic group alone. In addition, the strong relationship between hair cortisol and alopecia was noted in 2 but not the third facility. Friction with cage surfaces appeared to contribute to hair loss in 18 monkeys. These findings suggest that stress may be one of several factors related to hair loss in some captive nonhuman primates, although whether this relationship is causal or merely correlational is unclear. Moreover, the source of the additional cortisol in the hair of alopecic monkeys (that is, from the circulation or from local synthesis in the skin) remains to be determined.
Indexed as
Identifiers
24827567PMC4128563W2176387430What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.