Evidence map›Paper›PMID 24827086›Full record

ArticleJournal of autism and developmental disorders2014

White matter microstructure predicts autistic traits in attention-deficit/hyperactivity disorder.

Miriam Cooper, Anita Thapar, Derek K Jones

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mode of Anisotropy Reveals Global Diffusion Alterations in Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2016
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Miriam CooperChild and Adolescent Psychiatry Section, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Second Floor, Hadyn Ellis Building, Maindy Road, Cathays, Cardiff, CF24 4HQ, UK, cooperml1@cardiff.ac.uk.
Anita Thapar
Derek K Jones
Cardiff University · GB

Funding

Medical Research Council MR/L010305/1Wellcome Trust 096646
6 · The paper itself

Abstract

Traits of autism spectrum disorder (ASD) in children with attention-deficit/hyperactivity disorder (ADHD) have previously been found to index clinical severity. This study examined the association of ASD traits with diffusion parameters in adolescent males with ADHD (n = 17), and also compared WM microstructure relative to controls (n = 17). Significant associations (p < 0.05, corrected) were found between fractional anisotropy/radial diffusivity and ASD trait severity (positive and negative correlations respectively), mostly in the right posterior limb of the internal capsule/corticospinal tract, right cerebellar peduncle and the midbrain. No case-control differences were found for the diffusion parameters investigated. This is the first report of a WM microstructural signature of autistic traits in ADHD. Thus, even in the absence of full disorder, ASD traits may index a distinctive underlying neurobiology in ADHD.

Indexed as

AdolescentAnisotropyAttention Deficit Disorder with HyperactivityCase-Control StudiesChild Development Disorders, PervasiveDiffusion Magnetic Resonance ImagingHumansMaleNeuroimagingSeverity of Illness IndexWhite Matter

Identifiers

PMID24827086
PMCPMC4194020
OpenAlexW2169896339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.