ArticleJournal of cellular and molecular medicine2014
Differences in the expression of chromosome 1 genes between lung telocytes and other cells: mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells and lymphocytes.
Article in Journal of cellular and molecular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 70 citations in OpenAlex.
- Telocytes: history, origin, identification, structure, distribution, and functions.Histochemistry and cell biology · 2025Review
- Npc1 gene mutation impairs multilineage differentiation potential of hepatic telocytes in murine models.Cell biology and toxicology · 2025Article
- A transmission electron microscopy investigation suggests that telocytes, skeletal muscles, myoblasts, and stem cells in common carp (Cyprinus carpio) respond to salinity challenges.BMC veterinary research · 2024Article
- Roles of pulmonary telocytes in airway epithelia to benefit experimental acute lung injury through production of telocyte-driven mediators and exosomes.Cell biology and toxicology · 2023Article
- Morpho-functional changes of cardiac telocytes in isolated atrial amyloidosis in patients with atrial fibrillation.Scientific reports · 2021Article
- Fish telocytes and their relation to rodlet cells in ruby-red-fin shark (rainbow shark) Epalzeorhynchos frenatum (Teleostei: Cyprinidae).Scientific reports · 2020Article
- Morphological and immunohistochemical phenotype of TCs in the intestinal bulb of Grass carp and their potential role in intestinal immunity.Scientific reports · 2020Article
- Influence of gene modification in biological behaviors and responses of mouse lung telocytes to inflammation.Journal of translational medicine · 2019Article
- Telocytes constitute a widespread interstitial meshwork in the lamina propria and underlying striated muscle of human tongue.Scientific reports · 2019Article
- Morphological changes of telocytes in camel efferent ductules in response to seasonal variations during the reproductive cycle.Scientific reports · 2019Article
- Recently Discovered Interstitial Cell Population of Telocytes: Distinguishing Facts from Fiction Regarding Their Role in the Pathogenesis of Diverse Diseases Called "Telocytopathies".Medicina (Kaunas, Lithuania) · 2019Review
- Identification of Myocardial Telocytes and Bone Marrow Mesenchymal Stem Cells in Mice.Cell transplantation · 2018Article
- Effect of QSOX1 on cattle carcass traits as well as apoptosis and triglyceride production in bovine fetal fibroblasts and mammary epithelial cells.The Journal of veterinary medical science · 2018Article
- Calcium Signaling in Interstitial Cells: Focus on Telocytes.International journal of molecular sciences · 2017Review
- Telocytes and Their Extracellular Vesicles-Evidence and Hypotheses.International journal of molecular sciences · 2016Review
- Telocytes in female reproductive system (human and animal).Journal of cellular and molecular medicine · 2016Review
- Comparison of Chromosome 4 gene expression profile between lung telocytes and other local cell types.Journal of cellular and molecular medicine · 2016Article
- Telopodes of telocytes are influenced in vitro by redox conditions and ageing.Molecular and cellular biochemistry · 2015Article
- Skin telocytes versus fibroblasts: two distinct dermal cell populations.Journal of cellular and molecular medicine · 2015Article
- Global comparison of chromosome X genes of pulmonary telocytes with mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells, and lymphocytes.Journal of translational medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Telocytes (TCs) are a unique type of interstitial cells with specific, extremely long prolongations named telopodes (Tps). Our previous study showed that TCs are distinct from fibroblasts (Fbs) and mesenchymal stem cells (MSCs) as concerns gene expression and proteomics. The present study explores patterns of mouse TC-specific gene profiles on chromosome 1. We investigated the network of main genes and the potential functional correlations. We compared gene expression profiles of mouse pulmonary TCs, MSCs, Fbs, alveolar type II cells (ATII), airway basal cells (ABCs), proximal airway cells (PACs), CD8(+) T cells from bronchial lymph nodes (T-BL) and CD8(+) T cells from lungs (T-LL). The functional and feature networks were identified and compared by bioinformatics tools. Our data showed that on TC chromosome 1, there are about 25% up-regulated and 70% down-regulated genes (more than onefold) as compared with the other cells respectively. Capn2, Fhl2 and Qsox1 were over-expressed in TCs compared to the other cells, indicating that biological functions of TCs are mainly associated with morphogenesis and local tissue homoeostasis. TCs seem to have important roles in the prevention of tissue inflammation and fibrogenesis development in lung inflammatory diseases and as modulators of immune cell response. In conclusion, TCs are distinct from the other cell types.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.