Evidence map›Paper›PMID 24826893›Full record

ArticlePloS one2014

Detection of antibodies against Turkey astrovirus in humans.

Victoria A Meliopoulos, Ghazi Kayali, Andrew Burnham, Christine M Oshansky, Paul G Thomas, Gregory C Gray, Melinda A Beck, Stacey Schultz-Cherry

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A Review of Emerging Goose Astrovirus Causing Gout.BioMed research international · 2022
    Review
  10. Article
  11. Pathogenesis of Chicken Astrovirus Related Illnesses.Frontiers in veterinary science · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Astrovirus and the microbiome.Current opinion in virology · 2019
    Review
  19. Astrovirus evolution and emergence.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Victoria A MeliopoulosDepartment of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
Ghazi KayaliDepartment of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
Andrew BurnhamDepartment of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
Christine M OshanskyDepartment of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
Paul G ThomasDepartment of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
Gregory C GrayDepartment of Environmental and Global Health, College of Public Health Professions, University of Florida, Gainesville, Florida, United States of America.
Melinda A BeckDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Stacey Schultz-CherryDepartment of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
St. Jude Children's Research Hospital · USUniversity of Florida · USUniversity of North Carolina at Chapel Hill · US

Funding

Risk of Influenza Infection In A Vaccinated Obese PopulationR01AI078090 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BECK, MELINDA A. · 2009 to 2016
$4.5M
Prospective Studies of Avian Influenza Transmission in AsiaR01AI068803 · NIAID · UNIVERSITY OF IOWA · PI GRAY, GREGORY CHARLES · 2006 to 2010
$1.7M
NIAID NIH HHS HHSN266200700005CNIAID NIH HHS R01 AI068803NIAID NIH HHS R01 AI078090PHS HHS NIAID R01 AI068803
6 · The paper itself

Abstract

Astroviruses are a leading cause of gastroenteritis in mammals and birds worldwide. Although historically thought to be species-specific, increasing evidence suggests that astroviruses may cross species barriers. In this report, we used enzyme-linked immunosorbent assays to screen sera from three distinct human cohorts involved in influenza studies in Memphis, TN or Chapel Hill, NC, and Midwestern poultry abattoir workers for antibodies to turkey astrovirus type 2 (TAstV-2). Surprisingly, 26% of one cohort's population was TAstV-2 positive as compared to 0 and 8.9% in the other cohorts. This cohort was composed of people with exposure to turkeys in the Midwestern United States including abattoir workers, turkey growers, and non-occupationally exposed participants. The odds of testing positive for antibodies against turkey astrovirus among abattoir workers were approximately 3 times higher than the other groups. These studies suggest that people with contact to turkeys can develop serological responses to turkey astrovirus. Further work is needed to determine if these exposures result in virus replication and/or clinical disease.

Indexed as

Animal HusbandryAbattoirsAgricultureAmino Acid SequenceAnimalsAntibodies, ViralAstroviridae InfectionsAvastrovirusCapsid ProteinsCarrier StateHumansMidwestern United StatesMolecular Sequence DataTurkeysAntibodies, ViralCapsid Proteins

Identifiers

PMID24826893
PMCPMC4020816
OpenAlexW2058412361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.