Evidence map›Paper›PMID 24825947›Full record

ArticleBehavioural neurology2014

Prospective memory impairment and executive dysfunction in prefrontal lobe damaged patients: is there a causal relationship?

Giovanni A Carlesimo, Margherita di Paola, Lucia Fadda, Carlo Caltagirone, Alberto Costa

Open access · goldAbstract read
In one paragraph

Article in Behavioural neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giovanni A CarlesimoClinica Neurologica, Università Tor Vergata, Via Orazio Raimondo 18, 00173 Rome, Italy ; Department of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy.
Margherita di PaolaDepartment of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy ; Dipartimento di Medicina Clinica, Sanitá Pubblica, Scienze della Vita e dell'Ambiente, Piazzale Salvatore Tommasi 1, L'Aquila, Italy.
Lucia FaddaClinica Neurologica, Università Tor Vergata, Via Orazio Raimondo 18, 00173 Rome, Italy ; Department of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy.
Carlo CaltagironeClinica Neurologica, Università Tor Vergata, Via Orazio Raimondo 18, 00173 Rome, Italy ; Department of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy.
Alberto CostaDepartment of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy.
Fondazione Santa Lucia · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prospective memory (PM) construct is aimed at capturing cognitive operations involved in the successful accomplishment of delayed intentions. It is generally agreed that PM impairment occurs in patients with prefrontal lobes damage.

objectiveTo evaluate if there is a causal role of a deficit of executive abilities (failures of planning, set-shifting, selective attention, or working memory) over the PM impairment.

methodsWe report a detailed investigation of PM and executive abilities in two patients with posttraumatic damage to prefrontal lobes who complained from a reduced compliance with appointments and daily routines.

resultsLaboratory tests confirmed a difficulty in fulfilling delayed intentions in response to the occurrence of critical events and elapsed time. In one patient, PM impairment was associated with poor performance on tests investigating planning, working memory, and mental shifting. The other patient performed in the normal range on all executive tests.

conclusionsDespite the frequent claim of a dependence of PM deficits from executive dysfunction, the reported cases demonstrate that this is not necessarily the case. The results are discussed in the light of current hypotheses relating PM impairment to other deficits that commonly occur as a result of damage to the prefrontal lobes.

Indexed as

Executive FunctionMemory, EpisodicAdolescentAttentionBrain InjuriesHumansMaleMemory DisordersMemory, Short-TermNeuropsychological TestsPrefrontal CortexYoung Adult

Identifiers

PMID24825947
PMCPMC4006592
OpenAlexW2007575553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.