ArticleHippocampus2014
Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories.
Article in Hippocampus, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 96 citations in OpenAlex.
- Chronic Electroconvulsive Shock Disrupts Hippocampal Physiology and Impairs Associative Memory in Mice.Hippocampus · 2026Article
- Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time.Nature neuroscience · 2025Article
- Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical protein kinase C in the anterior cingulate cortex.Neuroscience · 2025Article
- Altered neuronal lactate dehydrogenase A expression affects cognition in a sex- and age-dependent manner.iScience · 2024Article
- Cellular mechanisms of contextual fear memory reconsolidation: Role of hippocampal SFKs, TrkB receptors and GluN2B-containing NMDA receptors.Psychopharmacology · 2024Article
- Environmental enrichment in middle age rats improves spatial and object memory discrimination deficits.Frontiers in behavioral neuroscience · 2024Article
- The spontaneous location recognition task for assessing spatial pattern separation and memory across a delay in rats and mice.Nature protocols · 2021Review
- The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling.International journal of molecular sciences · 2021Article
- IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR.Frontiers in cell and developmental biology · 2021Article
- Prolonged development of long-term potentiation at lateral entorhinal cortex synapses onto adult-born neurons.PloS one · 2021Article
- Functional neurogenesis over the years.Behavioural brain research · 2020Review
- Born this way: Hippocampal neurogenesis across the lifespan.Aging cell · 2019Review
- Brain-Derived Neurotrophic Factor Val66Met Polymorphism Is Associated With a Reduced ERP Component Indexing Emotional Recollection.Frontiers in psychology · 2019Article
- The role of adult hippocampal neurogenesis in brain health and disease.Molecular psychiatry · 2019Review
- Sex specific effects of pre-pubertal stress on hippocampal neurogenesis and behaviour.Translational psychiatry · 2018Article
- Delayed cognitive deficits can be alleviated by calcium antagonist nimodipine by downregulation of apoptosis following whole brain radiotherapy.Oncology letters · 2018Article
- Dietary influences on cognition.Physiology & behavior · 2018Article
- The mysteries of remote memory.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Intact memory for local and distal cues in male and female rats that lack adult neurogenesis.PloS one · 2018Article
- Neurogenesis Inhibition Prevents Enriched Environment to Prolong and Strengthen Social Recognition Memory, But Not to Increase BDNF Expression.Molecular neurobiology · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Successful memory involves not only remembering information over time but also keeping memories distinct and less confusable. The computational process for making representations of similar input patterns more distinct from each other has been referred to as "pattern separation." Although adult-born immature neurons have been implicated in this memory feature, the precise role of these neurons and associated molecules in the processing of overlapping memories is unknown. Recently, we found that brain-derived neurotrophic factor (BDNF) in the dentate gyrus is required for the encoding/consolidation of overlapping memories. In this study, we provide evidence that consolidation of these "pattern-separated" memories requires the action of BDNF on immature neurons specifically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.