Evidence map›Paper›PMID 24825338›Full record

ArticleSexually transmitted diseases2014

Impact of a routine, opt-out HIV testing program on HIV testing and case detection in North Carolina sexually transmitted disease clinics.

Pamela W Klein, Lynne C Messer, Evan R Myers, David J Weber, Peter A Leone, William C Miller

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Sexually transmitted diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Pamela W KleinFrom the *Center for AIDS Intervention Research, Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI; †Department of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, NC; ‡School of Community Health, College of Urban and Public Affairs, Portland State University, Portland, OR; §Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC; and ¶HIV/STD Prevention and Care Branch, North Carolina Division of Public Health, Raleigh, NC.
Lynne C Messer
Evan R Myers
David J Weber
Peter A Leone
William C Miller
Duke Medical Center · USMedical College of Wisconsin · USNorth Carolina Division of Public Health · USOffice of Infectious Diseases · USPortland State University · US

Funding

Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
NRSA POSTDOCTORAL TRAINING PROGRAM IN HIV PREVENTION REST32MH019985 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI GALLETLY, CAROL L · 1996 to 2017
$2.4M
NCHHSTP CDC HHS PS 12-1201NIAID NIH HHS T32 AI070114NIAID NIH HHS T32-AI070114NIMH NIH HHS T32 MH019985NIMH NIH HHS T32-MH19985
6 · The paper itself

Abstract

backgroundThe impact of routine, opt-out HIV testing programs in clinical settings is inconclusive. The objective of this study was to estimate the impact of an expanded, routine HIV testing program in North Carolina sexually transmitted disease (STD) clinics on HIV testing and case detection.

methodsAdults aged 18 to 64 years who received an HIV test in a North Carolina STD clinic from July 1, 2005, through June 30, 2011, were included in this analysis, dichotomized at the date of implementation on November 1, 2007. HIV testing and case detection counts and rates were analyzed using interrupted time series analysis and Poisson and multilevel logistic regression.

resultsPreintervention, 426 new HIV-infected cases were identified from 128,029 tests (0.33%), whereas 816 new HIV-infected cases were found from 274,745 tests postintervention (0.30%). Preintervention, HIV testing increased by 55 tests per month (95% confidence interval [CI], 41-72), but only 34 tests per month (95% CI, 26-42) postintervention. Increases in HIV testing rates were most pronounced in women and non-Hispanic whites. A slight preintervention decline in case detection was mitigated by the intervention (mean difference, 0.01; 95% CI, -0.02 to 0.05). Increases in case detection rates were observed among women and non-Hispanic blacks.

conclusionsThe impact of a routine HIV screening in North Carolina STD clinics was marginal, with the greatest benefit among persons not traditionally targeted for HIV testing. The use of a preintervention comparison period identified important temporal trends that otherwise would have been ignored.

Indexed as

Mass ScreeningAdolescentAdultContact TracingFemaleHIV InfectionsHumansInterrupted Time Series AnalysisLogistic ModelsMaleMiddle AgedNorth CarolinaOutcome Assessment, Health CarePopulation Surveillance

Identifiers

PMID24825338
PMCPMC5056640
OpenAlexW1972611518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.