Trial reportMedicine and science in sports and exercise2014
Early rehabilitative exercise training in the recovery from pediatric burn.
Trial report in Medicine and science in sports and exercise, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06654908 (Insulin Resistance and Resisted Exercise Post Burn), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Insulin Resistance and Resisted Exercise Post Burn
Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Effectiveness of physiotherapist-led exercise interventions for burn rehabilitation: A systematic review and meta-analysis.PloS one · 2024Pooled it
- The effects of resistance training on children with burns: a meta-analysis.Pediatric surgery international · 2021Pooled it
- Systematic review of clinical outcome reporting in randomised controlled trials of burn care.BMJ open · 2019Pooled it
- Quantification of an Exercise Rehabilitation Program for Severely Burned Children: The Standard of Care at Shriners Hospitals for Children®-Galveston.Journal of burn care & research : official publication of the American Burn Association · 2018Guideline
- Comparison of Six-Minute Walk Test and Modified Bruce Treadmill Test in Paediatric Patients With Severe Burns: A Cross-Over Study.Journal of rehabilitation medicine · 2022Trial
- The effects of short bouts of ergometric exercise for severely burned children in intensive care: A randomized controlled trial.Clinical rehabilitation · 2022Trial
- Resting β-Adrenergic Blockade Does Not Alter Exercise Thermoregulation in Children With Burn Injury: A Randomized Control Trial.Journal of burn care & research : official publication of the American Burn Association · 2018Trial
- Short-term metformin and exercise training effects on strength, aerobic capacity, glycemic control, and mitochondrial function in children with burn injury.American journal of physiology. Endocrinology and metabolism · 2018Trial
- Propranolol and Oxandrolone Therapy Accelerated Muscle Recovery in Burned Children.Medicine and science in sports and exercise · 2018Trial
- Effects of different duration exercise programs in children with severe burns.Burns : journal of the International Society for Burn Injuries · 2017Trial
- Effects of whole-body vibration exercise on bone mineral content and density in thermally injured children.Burns : journal of the International Society for Burn Injuries · 2016Trial
- The effect of lower body burns on physical function.Burns : journal of the International Society for Burn Injuries · 2015Trial
- Key Exercise Concepts in the Rehabilitation from Severe Burns.Physical medicine and rehabilitation clinics of North America · 2023Review
- [Research advances on the application of rehabilitation exercise training in pediatric burn rehabilitation].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Review
- Effects of Aerobic Exercise in the Intensive Care Unit on Patient-Reported Physical Function and Mental Health Outcomes in Severely Burned Children-A Multicenter Prospective Randomized Trial.Journal of personalized medicine · 2023Article
- Current understanding of the chronic stress response to burn injury from human studies.Burns & trauma · 2023Review
- Rehabilitative Exercise Training for Burn Injury.Sports medicine (Auckland, N.Z.) · 2021Review
- A narrative review of skeletal muscle atrophy in critically ill children: pathogenesis and chronic sequelae.Translational pediatrics · 2021Review
- [Research advances on the effect of resistance training on the rehabilitation of burned children].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021Review
- Low Vibrational Training as an Additional Intervention for Postural Balance, Balance Confidence and Functional Mobility in Type 2 Diabetic Patients with Lower Limb Burn Injury: A Randomized Clinical Trial.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe purpose of this study was to determine the effects of early outpatient exercise on muscle mass, function, and fractional synthetic rate in severely burned children.
methodsForty-seven children with ≥40% total body surface area burn performed a 12-wk standard of care rehabilitation (SOC, n = 23) or rehabilitative exercise training (RET, n = 24) immediately after hospital discharge. Dual-energy x-ray absorptiometry was used to assess lean body mass (LBM) at discharge, posttreatment, and 12 months post-burn. Muscle function was evaluated with a Biodex Isokinetic Dynamometer, and peak aerobic fitness (V˙O2peak) was measured using a modified Bruce treadmill protocol posttreatment. Stable isotope infusion studies were performed in a subset of patients (SOC, n = 13; RET, n = 11) at discharge and posttreatment to determine mixed-muscle fractional synthetic rate.
resultsRelative peak torque (RET, 138 ± 9 N·m·kg, vs SOC, 106 ± 9 N·m·kg) and V˙O2peak (RET, 32 ± 1 mL·kg·min, vs SOC, 28 ± 1 mL·kg·min) were greater at posttreatment with RET compared with those with SOC. In addition, RET increased whole-body (9% ± 2%) and leg (17% ± 3%) LBM compared with SOC. Furthermore, the percentage change in whole-body (18% ± 3%) and leg (31% ± 4%) LBM from discharge to 12 months post-burn was greater with RET compared to SOC. Muscle fractional synthetic rate decreased from discharge to posttreatment in both groups (6.9% ± 1.1% per day vs 3.4 ± 0.4% per day); however, no differences were observed between treatment groups at each time point.
conclusionsEarly outpatient exercise training implemented at hospital discharge represents an effective intervention to improve muscle mass and function after severe burn injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.