Trial reportPloS one2014
Efficacy of enhanced HIV counseling for risk reduction during pregnancy and in the postpartum period: a randomized controlled trial.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of HIV Posttest Support for ANC in South Africa
Re-enrolling Young South African Mothers in School as a Social Vaccine Against HIV Transmission
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Sexual behaviour change following HIV testing services: a systematic review and meta-analysis.Journal of the International AIDS Society · 2020Pooled it
- Integrating prevention interventions for people living with HIV into care and treatment programs: a systematic review of the evidence.Journal of acquired immune deficiency syndromes (1999) · 2015Pooled it
- Safer disclosure of HIV serostatus for women living with HIV who experience or fear violence: a systematic review.Journal of the International AIDS Society · 2015Pooled it
- Diagnosis and Disclosure of HIV Status: Implications for Women's Risk of Physical Partner Violence in the Postpartum Period.Journal of acquired immune deficiency syndromes (1999) · 2016Trial
- Mapping Psychosocial Interventions for Mental Health and Well-Being Among Pregnant Women Living with HIV: A Scoping Review.Journal of multidisciplinary healthcare · 2026Review
- Aetiological testing compared with syndromic management for sexually transmitted infections in HIV-infected pregnant women in South Africa: a non-randomised prospective cohort study.BJOG : an international journal of obstetrics and gynaecology · 2021Article
- Patterns of Intimate Partner Violence Victimization Among South African Women and Their Relation to Emotional Distress During Pregnancy and Postpartum.Journal of interpersonal violence · 2021Article
- Intimate partner violence and postpartum emotional distress among South African women: Moderating effects of resilience and vulnerability factors.Global public health · 2020Article
- Describing Relationship Characteristics and Postpartum HIV Risk Among Adolescent, Young Adult, and Adult Women in South Africa.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020Article
- Article
- Implementation of postnatal care for HIV-positive mothers in the Free State: Nurses' perspectives.African journal of primary health care & family medicine · 2019Article
- Agents of change among people living with HIV and their social networks: stepped-wedge randomised controlled trial of theBMJ global health · 2019Article
- Sexual Behaviors of Human Immunodeficiency Virus-Infected Pregnant Women and Factors Associated With Sexually Transmitted Infection in South Africa.Sexually transmitted diseases · 2018Article
- Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol.Contemporary clinical trials · 2018Article
- HIV Status Disclosure Among Postpartum Women in Zambia with Varied Intimate Partner Violence Experiences.AIDS and behavior · 2018Article
- Prevalence, risk factors, and pregnancy outcomes of cervical cell abnormalities in the puerperium in a hyperendemic HIV setting.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2018Article
- Dual Method Use among Postpartum HIV-Infected and HIV-Uninfected Malawian Women: A Prospective Cohort Study.Infectious diseases in obstetrics and gynecology · 2017Article
- Patterns of Contraceptive Adoption, Continuation, and Switching after Delivery among Malawian Women.PloS one · 2017Article
- Legal knowledge, needs, and assistance seeking among HIV positive and negative women in Umlazi, South Africa.BMC international health and human rights · 2016Article
- Social support among HIV-positive and HIV-negative adolescents in Umlazi, South Africa: changes in family and partner relationships during pregnancy and the postpartum period.BMC pregnancy and childbirth · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
introductionPregnancy and the postpartum period present important intervention opportunities. Counseling can leverage the motivation women have during this time to change behaviors that may negatively affect their health and the heath of their infants.
methodsPregnant women attending an antenatal clinic in South Africa were randomly allocated to treatment (n=733) and control arms (n=747). Treatment arm participants received enhanced HIV pre- and post-test counseling, legal support and access to support groups at baseline, which occurred at the first antenatal visit, and then six and ten weeks postpartum. Control arm participants received standard HIV testing and counseling (HTC) and two postpartum attention control sessions. Outcomes were incidence of sexually transmitted infection (STI) by 14 weeks postpartum and past 30-day inconsistent condom use at 14 weeks and 9 months postpartum.
resultsThere were no intervention effects on incident STIs for either HIV-negative (adjusted risk ratio (aRR) 1.01, 95% CI 0.71-1.44) or HIV-positive participants (aRR 0.86, 95% CI 0.61-1.23). The intervention was associated with a 28% decrease in risk of past 30-day inconsistent condom use at nine-months among HIV-negative women (aRR 0.72,95% CI 0.59-0.88), but did not affect inconsistent condom use among HIV-positive women (aRR1.08; 95% CI 0.67-1.75). DISCUSSION: An enhanced counseling intervention during pregnancy and the postpartum period can lead to reductions in inconsistent condom use among HIV-negative women. Results underscore the importance of the counseling that accompanies HIV HTC. More work is needed to understand how to promote and sustain risk reduction among HIV-positive women.
trial registrationClinicalTrials.gov NCT01683461.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.