Evidence map›Paper›PMID 24823985›Full record

ArticleJournal of the American Geriatrics Society2014

Pain characteristics associated with the onset of disability in older adults: the maintenance of balance, independent living, intellect, and zest in the Elderly Boston Study.

Laura H P Eggermont, Suzanne G Leveille, Ling Shi, Dan K Kiely, Robert H Shmerling, Rich N Jones, Jack M Guralnik, Jonathan F Bean

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02217540 (Mulligan Concept Mobilisation With Movement for Shoulder Dysfunction in Older Adults- A Pilot Randomised Clinical Trial), which is not on this map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02217540 nacompletednot on this map

Mulligan Concept Mobilisation With Movement for Shoulder Dysfunction in Older Adults- A Pilot Randomised Clinical Trial

TypeinterventionalSponsorUniversity of AlcalaRan2012 to 2013Enrolled44ConditionsDisorder of ShoulderArmsStandard protocol, Mulligan Concept Mobilisation with Movement
3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. From age to frailty: redefining chronic pain characterization.Aging clinical and experimental research · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura H P EggermontDepartment of Clinical Neuropsychology, VU University, Amsterdam, the Netherlands.
Suzanne G Leveille
Ling Shi
Dan K Kiely
Robert H Shmerling
Rich N Jones
Jack M Guralnik
Jonathan F Bean

Funding

VITAMIN D NUTRITION IN THE INSTITUTIONALIZED ELDERLYP01AG004390 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI CHENG, DEBBIE M. · 1985 to 2008
$13.2M
Attention Demands of Chronic Pain and Risk for Falls in Older AdultsR01AG041525 · NIA · UNIVERSITY OF MASSACHUSETTS BOSTON · PI LEVEILLE, SUZANNE G. · 2011 to 2015
$3.0M
A Research Mentoring Program in the Rehabilitative Care of Older AdultsK24HD070966 · NICHD · SPAULDING REHABILITATION HOSPITAL · PI BEAN, JONATHAN F · 2012 to 2016
$793k
NIA NIH HHS P01 AG004390NIA NIH HHS P01AG004390NIA NIH HHS R01 AG041525NIA NIH HHS R01AG041525-01NICHD NIH HHS 1K24HD070966-01NICHD NIH HHS K24 HD070966
6 · The paper itself

Abstract

objectivesTo determine the effects of chronic pain on the development of disability and decline in physical performance over time in older adults.

designLongitudinal cohort study with 18 months of follow-up.

settingUrban and suburban communities.

participantsCommunity-dwelling older adults aged 65 and older (N = 634). MEASUREMENTS: Chronic pain assessment consisted of musculoskeletal pain locations and pain severity and pain interference according to the subscales of the Brief Pain Inventory. Disability was self-reported as any difficulty in mobility and basic and instrumental activities of daily living (ADLs, IADLs). Mobility performance was measured using the Short Physical Performance Battery (SPPB). Relationships between baseline pain and incident disability in 18 months were determined using risk ratios (RRs) from multivariable Poisson regression models.

resultsAlmost 65% of participants reported chronic musculoskeletal pain at baseline. New onset of mobility difficulty at 18 months was strongly associated with baseline pain distribution: 7% (no sites), 18% (1 site), 24% (multisite), and 39% (widespread pain, P-value for trend < .001). Similar graded effects were found for other disability measures. Elderly adults with multisite or widespread pain had at a risk of onset of mobility difficulty at least three times as great as that of their peers without pain after adjusting for disability risk factors (multisite pain: risk ratio (RR) = 2.95, 95% confidence interval (CI) 1.58-5.50; widespread pain: RR = 3.57, 95% CI = 1.71-7.48). Widespread pain contributed to decline in mobility performance (1-point decline in SPPB, RR = 1.47, 95% CI = 1.08-2.01). Similar associations were found for baseline pain interference predicting subsequent mobility decline and ADL and IADL disability. Weaker and less-consistent associations were observed with pain severity.

conclusionOlder community-dwelling adults living with chronic pain in multiple musculoskeletal locations have a substantially greater risk for developing disability over time and for clinically meaningful decline in mobility performance than those without pain.

Indexed as

CognitionDisability EvaluationIndependent LivingPersons with DisabilitiesPostural BalanceQuality of LifeAgedAged, 80 and overChronic PainCohort StudiesFemaleHumansMaleMiddle Agedactivities of daily livingmobility limitationolder adultswidespread chronic pain

Identifiers

PMID24823985
PMCPMC4057984

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.