ArticleMolecular plant pathology2014
Heat shock protein 70 is necessary for Rice stripe virus infection in plants.
Article in Molecular plant pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 99 citations in OpenAlex.
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- Systematic analysis of Heat Shock Protein 70 (HSP70) gene family in radish and potential roles in stress tolerance.BMC plant biology · 2024Article
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- Comparative RNA-seq analysis of resistant and susceptible banana genotypes reveals molecular mechanisms in response to banana bunchy top virus (BBTV) infection.Scientific reports · 2023Article
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- Identification and characterization of pleiotropic and epistatic QDRL conferring partial resistance to Pythium irregulare and P. sylvaticum in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
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- Characterization of maize miRNAs responsive to maize Iranian mosaic virus infection.3 Biotech · 2022Article
- Field application of nanoliposomes delivered quercetin by inhibiting specific hsp70 gene expression against plant virus disease.Journal of nanobiotechnology · 2022Article
- Resistance induction based on the understanding of molecular interactions between plant viruses and host plants.Virology journal · 2021Review
- The Bunyavirales: The Plant-Infecting Counterparts.Viruses · 2021Review
- Comparative proteomic analysis of Nicotiana benthamiana plants under Chinese wheat mosaic virus infection.BMC plant biology · 2021Article
- Volatile Compounds FromFrontiers in microbiology · 2021Article
- The Lipid Transfer Protein 1 fromViruses · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat shock proteins 70 (HSP70s) are a highly conserved family of genes in eukaryotes, and are involved in a remarkable variety of cellular processes. In many plant positive-stranded RNA viruses, HSP70 participates in the construction of a viral replication complex and plays various roles during viral infection. Here, we found increased expression of HSP70 following infection by Rice stripe virus (RSV), a negative-stranded RNA virus, in both rice (the natural host) and Nicotiana benthamiana (an experimental host). Heat treatment of N. benthamiana (Nb) plants enhanced viral infection, whereas RSV infection was retarded and viral RNAs accumulated at a low level when HSP70 was silenced. In both bimolecular fluorescence complement and in vitro pull-down assays, the N-terminus of RSV RNA-dependent RNA polymerase (RdRp) interacted and co-localized with the HSP70s of both plants (OsHSP70 and NbHSP70). The localization of the N-terminus of RdRp when expressed alone was not obviously different from when it was co-expressed with OsHSP or NbHSP, and vice versa. RSV infection also had no effect on the localization of host HSP70. These results demonstrate that host HSP70 is necessary for RSV infection and probably plays a role in viral replication by interacting with viral RdRp, which provides the first evidence of an interacting host protein related to RSV replication, which has been little studied to date.
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